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PHR1031

α-生育酚

Name: α-生育酚
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

(±)-α-生育酚, DL-全-rac-α-生育酚, 维生素E

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关于此项目

经验公式（希尔记法）:

C₂₉H₅₀O₂

化学文摘社编号:

10191-41-0

分子量:

430.71

NACRES:

NA.24

PubChem Substance ID:

329823061

eCl@ss:

34058016

UNSPSC Code:

41116107

EC Number:

233-466-0

MDL number:

MFCD00006848

Beilstein/REAXYS Number:

94012

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属性

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. T1550000, traceable to USP 1667600

API family

tocopherol

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

density

0.950 g/mL at 20 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

说明

General description

α-生育酚是强大的生物抗氧化剂，是维生素E在人体中最活跃的形式。
用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。

Application

α-生育酚可作为药物参考标准品，使用流动注射化学发光技术定量药物制剂中的分析物。

这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。

Analysis Note

这些二级标准品可追溯至USP、EP（PhEur）和BP一级标准品。

Other Notes

想要查看本品的分析证书示例，请在下框中输入LRAB3718。这只是一个示例证书，可能与您收到的批次不符。

该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

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pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

存储类别

10 - Combustible liquids

分析证书(COA)

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实验方案

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

Flow-injection determination of retinol and tocopherol in pharmaceuticals with acidic potassium permanganate chemiluminescence

Waseem A, et al.

Analytical Sciences, 25(3), 407-412 (2009)

Simultaneous determination of retinol and alpha-tocopherol in serum or plasma by liquid chromatography

Catignani LG and Bieri GJ

Clinical Chemistry, 29, 708-712 (1983)

Protective effects of different antioxidants against cadmium induced oxidative damage in rat testis and prostate tissues.

Sarwat Jahan et al.

Systems biology in reproductive medicine, 60(4), 199-205 (2014-04-25)

The present study was performed to determine the effects of different antioxidants on testicular histopathology and oxidative damage induced by cadmium (Cd) in rat testis and prostate. Twenty five rats were equally divided into five groups (n = 5/group). The control group

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全球贸易项目编号

货号	GTIN
PHR1031-500MG	04061835237012