PHR1123
肉豆蔻酸异丙酯
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
十四碳酸异丙酯, 十四酸异丙酯
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线性分子式:
CH3(CH2)12COOCH(CH3)2
化学文摘社编号:
分子量:
270.45
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
203-751-4
Beilstein/REAXYS Number:
1781127
MDL number:
eCl@ss:
39022421
Quality Level
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to Ph. Eur. I0750000, traceable to USP 1350400
API family
isopropyl myristate
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
refractive index
n20/D 1.434 (lit.)
bp
193 °C/20 mmHg (lit.)
mp
~3 °C (lit.)
density
0.85 g/mL at 25 °C (lit.)
application(s)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
CCCCCCCCCCCCCC(=O)OC(C)C
InChI
1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChI key
AXISYYRBXTVTFY-UHFFFAOYSA-N
General description
Isopropyl myristate is an ester of isopropyl alcohol myristic acid. It is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. It also finds applications as a flavoring agent in the food industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analysis Note
These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7001 in the slot below. This is an example certificate only and may not be the lot that you receive.
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存储类别
10 - Combustible liquids
wgk
awg
flash_point_f
>302.0 °F
flash_point_c
> 150 °C
CRC Handbook of Food, Drug, and Cosmetic Excipients (1992)
Ji Zhang et al.
International journal of pharmaceutics, 421(1), 34-44 (2011-10-01)
In this study, microemulsion microstructures, key formulation variables, and their relationship to drug transdermal permeation enhancement were investigated. A microemulsion system with high water soluble capacity was developed, using isopropyl myristate, Labrasol, and Cremophor EL as oil, surfactant, and co-surfactant
Qingping Tian et al.
International journal of pharmaceutics, 426(1-2), 202-210 (2012-01-26)
To improve the skin permeation of naproxen with larger dosage, microemulsion with high content of naproxen was investigated for transdermal delivery and its solubilization mechanism was studied. Naproxen micoremulsions composed of 4% isopropyl myristate, 18% Tween 80, 18% ethanol and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| PHR1123-1G | 04061835233175 |