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X4251

XTT 钠盐

Name: XTT 钠盐
Brand: SIAL

analytical standard, ≥90%

别名:

2,3-双(2-甲氧基-4-硝基-5-磺苯基)-2H-四氮唑-5-甲酰苯胺内盐

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关于此项目

经验公式（希尔记法）:

C₂₂H₁₆N₇NaO₁₃S₂

化学文摘社编号:

111072-31-2

分子量:

673.52

NACRES:

NA.24

PubChem Substance ID:

329830806

UNSPSC Code:

41116107

MDL number:

MFCD00083517

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属性

grade

analytical standard

Quality Level

100

assay

≥90%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].COc1cc(c(cc1-n2nc(n[n+]2-c3cc(c(cc3OC)[N+]([O-])=O)S([O-])(=O)=O)C(=O)Nc4ccccc4)S([O-])(=O)=O)[N+]([O-])=O

InChI

1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);/q;+1/p-1

InChI key

JACYMBNQPPWQML-UHFFFAOYSA-M

说明

Application

XTT可与吩嗪硫酸甲酯（PMS）联合使用，用于筛选人肿瘤细胞系。四唑染料也被用于真菌细胞损伤研究、葡萄球菌的抗菌敏感性测试，以及念珠菌生物膜研究。XTT检测法的局限性也有报道。

可用于艾滋病和癌症检测。

有关合适的仪器技术的更多信息，请参阅产品′的分析证书。联系技术服务部以获得进一步支持。

Biochem/physiol Actions

在活细胞中，XTT被代谢还原，生成可比色的水溶性甲臜产物。

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pictograms

GHS02

signalword

Danger

hcodes

H242

pcodes

P210 - P234 - P235 - P240 - P370 + P378 - P403

Hazard Classifications

Self-react. C

supp_hazards

EUH044

存储类别

4.1A - Other explosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Parsons, J.L., et al.

Journal of Heterocyclic Chemistry, 25, 911-911 (1988)

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.

D A Scudiero et al.

Cancer research, 48(17), 4827-4833 (1988-09-01)

We have previously described the application of an automated microculture tetrazolium assay (MTA) involving dimethyl sulfoxide solubilization of cellular-generated 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)-formazan to the in vitro assessment of drug effects on cell growth (M.C. Alley et al., Proc. Am. Assoc.

Squalene Stimulates a Key Innate Immune Cell to Foster Wound Healing and Tissue Repair.

Cristina Sánchez-Quesada et al.

Evidence-based complementary and alternative medicine : eCAM, 2018, 9473094-9473094 (2018-10-27)

Anti-inflammatory effects of virgin olive oil (VOO) have been described recently, along with its wound healing effect. One of the main minor compounds found in VOO is squalene (SQ), which also possesses preventive effects against skin damage and anti-inflammatory properties.

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全球贸易项目编号

货号	GTIN
X4251-100MG	04061835513741
X4251-500MG	04061835513758