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Merck
CN

Y0001183

三乙醇胺杂质B

European Pharmacopoeia (EP) Reference Standard

别名:

二乙醇胺, 2,2′-亚氨基二乙醇, 二(2-羟乙基)胺

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关于此项目

线性分子式:
HN(CH2CH2OH)2
化学文摘社编号:
分子量:
105.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
605315
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grade

pharmaceutical primary standard

vapor density

3.6 (vs air)

vapor pressure

<0.98 atm ( 100 °C)

API family

trolamine

autoignition temp.

689 °F

expl. lim.

10.6 %

manufacturer/tradename

EDQM

refractive index

n20/D 1.477 (lit.)

bp

217 °C/150 mmHg (lit.)

mp

28 °C (lit.)

density

1.097 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OCCNCCO

InChI

1S/C4H11NO2/c6-3-1-5-2-4-7/h5-7H,1-4H2

InChI key

ZBCBWPMODOFKDW-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Trolamine impurity B EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Oral

target_organs

Kidney,Liver,Blood

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

280.4 °F - closed cup

flash_point_c

138 °C - closed cup

法规信息

危险化学品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Choline deficiency associated with diethanolamine carcinogenicity.
Paul M Newberne
Toxicological sciences : an official journal of the Society of Toxicology, 67(1), 1-3 (2002-04-19)
M-L Metzger et al.
Clinical and experimental immunology, 179(2), 256-264 (2014-09-25)
Common variable immunodeficiency (CVID) encompasses a heterogeneous group of antibody deficiencies characterized by susceptibility to recurrent infections and sequelae, including bronchiectasis. We investigated the relevance of the lectin complement pathway in CVID patients by analysing ficolin-2 and ficolin-3 serum levels
Hon-Wing Leung et al.
Regulatory toxicology and pharmacology : RTP, 43(3), 260-271 (2005-09-29)
Diethanolamine (DEA) is a chemical used widely in a number of industries and is present in many consumer products. Studies by the National Toxicology Program (NTP) have indicated that lifetime dermal exposure to DEA increased the incidence and multiplicity of



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