01930
腺苷 5′-单磷酸 二钠盐
≥99.0% (HPLC)
别名:
5′-AMP二钠盐,, 腺苷酸二钠盐, 5′-AMP-Na2
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关于此项目
经验公式（希尔记法）:
C10H12N5Na2O7P
化学文摘社编号:
分子量:
391.18
PubChem Substance ID:
eCl@ss:
32160414
UNSPSC Code:
41106305
NACRES:
NA.51
EC Number:
224-961-2
MDL number:
Beilstein/REAXYS Number:
3586732
Assay:
≥99.0% (HPLC)
Biological source:
microbial (Candida utilis), synthetic
Form:
powder
Quality Level
biological source
microbial (Candida utilis), synthetic
assay
≥99.0% (HPLC)
form
powder
optical activity
[α]20/D −43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)
impurities
≤26% water
InChI
1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
InChI key
QGXLVXZRPRRCRP-IDIVVRGQSA-L
Application
5′-单磷酸腺苷二钠盐已用于：
- 作为可溶性有机磷（DOP）化合物，以研究在大肠杆菌裂解物中的水解速率
- 诱导Fura2成骨细胞（C2-OB）钙反应
- 在分离、培养和鉴定胶质瘤干细胞（GSC）的培养基中作为核苷酸代谢物
腺苷5′-一磷酸（5′-AMP）在自然界中具有许多用途。5′-AMP是一类蛋白激酶[AMP活化蛋白激酶（AMPK）]的激活剂。它可以用作多种酶的底物，如AMP-胸苷激酶(EC 2.7.1.114)、AMP脱氨酶(EC 3.5.4.6)和5′-核苷酸酶(EC 3.1.3.5)。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Nicholas Mikolajewicz et al.
Biophysical journal, 116(10), 2009-2022 (2019-05-06)
The skeleton constantly interacts and adapts to the physical world. We have previously reported that physiologically relevant mechanical forces lead to small repairable membrane injuries in bone-forming osteoblasts, resulting in release of ATP and stimulation of purinergic (P2) calcium responses
5′-AMP-activated protein kinase is inactivated by adrenergic signalling in adult cardiac myocytes.
Tsuchiya Y, Denison FC, et al.
Bioscience Reports, 32(2), 197-213 (2011)
Aric H Mine et al.
Frontiers in microbiology, 12, 641700-641700 (2021-04-27)
The availability of phosphorus limits primary production in large regions of the oceans, and marine microbes use a variety of strategies to overcome this limitation. One strategy is the production of alkaline phosphatase (APase), which allows hydrolysis of larger dissolved
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C81004-100G | 04061838353351 |
| C81004-25G | 04061833521694 |
| 01930-25G | 04061833615997 |
| 01930-5G | 04061838611772 |