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Merck
CN

307M-9

Cytokeratin 7 (OV-TL 12/30) Mouse Monoclonal Antibody

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
OV-TL 12/30, monoclonal
Application:
IHC (p)
Citations:
8
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

diluted ascites fluid

antibody product type

primary antibodies

clone

OV-TL 12/30, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (307M-94), vial of 0.5 mL concentrate (307M-95), bottle of 1.0 mL predilute (307M-97), vial of 1.0 mL concentrate (307M-96), bottle of 7.0 mL predilute (307M-98)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

lung adenocarcinoma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... KRT7(3855)

General description

Anti-cytokeratin 7 reacts with proteins that are found in most ductal, glandular, transitional, and biliary duct epithelial cells. Cytokeratin 7 (CK7) labeling can help distinguish between lung, breast carcinomas, and urothelial carcinomas that are typically stain positive, and colon and prostate carcinomas that typically lack CK7 expression. CK7 is a common marker of primary lung adenocarcinomas and is observed in other primary lung carcinomas and non-pulmonary carcinomas. Anti-cytokeratin 7 has also been useful in the differential diagnosis of ovarianneoplasms.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

Cytokeratin 7 Positive Control Slides, Product No. 307S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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Preetha Ramalingam et al.
Annals of diagnostic pathology, 7(2), 112-119 (2003-04-26)
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To assess cytokeratin (CK) and thyroid transcription factor (TTF)-1 expression in primary epithelial lung tumours by comparison with non-pulmonary carcinomas and to correlate it with their histological type and grade. Immunohistochemistry using antibodies against CKs 5/6, 7, 19, 20 and



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