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Merck
CN

90469

(RS)-甲羟戊酸 锂盐

≥96.0% (GC)

别名:

(±)-MVA-Li, rac.-MVA-Li, 锂 (±)-3,5-二羟基-3-甲基-戊酸酯, 锂 (±)-3,5-二羟基-3-甲基戊酸酯

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关于此项目

经验公式(希尔记法):
C6H11O4 · xLi+
化学文摘社编号:
分子量:
147.15 (free acid basis)
MDL number:
UNSPSC Code:
12352107
NACRES:
NA.25
Assay:
≥96.0% (GC)
Form:
solid
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Quality Level

assay

≥96.0% (GC)

form

solid

composition

lithium, 2.2-4.7%

storage temp.

2-8°C

SMILES string

OC(CCO)(CC(=O)O)C

InChI

1S/C6H12O4/c1-6(10,2-3-7)4-5(8)9/h7,10H,2-4H2,1H3,(H,8,9)

InChI key

KJTLQQUUPVSXIM-UHFFFAOYSA-N

Biochem/physiol Actions

甲羟戊酸途径的代谢产物,在甾醇、多萜醇、血红素和泛醌的生物合成中起关键作用。在疾病肿瘤、自身免疫性疾病、动脉粥样硬化和阿尔茨海默病,以及遗传缺陷的甲羟戊酸激酶等研究领域受到关注。

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Andréa Hemmerlin
Plant science : an international journal of experimental plant biology, 203-204, 41-54 (2013-02-19)
Identification of regulatory enzymes is fundamental for engineering metabolic pathways such as the isoprenoid one. All too often, investigation of gene expression remains the major trend in unraveling regulation mechanisms of the isoprenoid cytosolic mevalonate and the plastid-localized methylerythritol phosphate
Jinbo Gao et al.
Biochimica et biophysica acta, 1830(6), 3635-3642 (2013-02-23)
Mevalonate pathway is an important cellular metabolic pathway present in all higher eukaryotes and many bacteria. Four enzymes in mevalonate pathway, including MVK, PMK, MDD, and FPPS, play important regulatory roles in cholesterol biosynthesis and cell proliferation. The following methods
Jordi Pérez-Gil et al.
The Biochemical journal, 452(1), 19-25 (2013-04-26)
Isoprenoids are a large family of compounds synthesized by all free-living organisms. In most bacteria, the common precursors of all isoprenoids are produced by the MEP (methylerythritol 4-phosphate) pathway. The MEP pathway is absent from archaea, fungi and animals (including



全球贸易项目编号

货号GTIN
90469-10MG04061832393810
90469-250MG04061832393827
90469-50MG04061832393834