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7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素

Name: 7-二乙氨基-3-（4-马来酰亚胺苯基）-4-甲基香豆素
Brand: SIGMA

suitable for fluorescence, BioReagent, ≥90% (HPCE)

别名:

1 H -吡咯-2,5-二酮，1-（4-（7-（二乙氨基）-4-甲基-2-氧代-2 H -1-苯并吡喃-3-基）苯基）-, CPM

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关于此项目

经验公式（希尔记法）:

C₂₄H₂₂N₂O₄

化学文摘社编号:

76877-33-3

分子量:

402.44

NACRES:

NA.32

PubChem Substance ID:

57653774

UNSPSC Code:

12171500

MDL number:

MFCD00077334

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属性

product line

BioReagent

Quality Level

100

assay

≥90% (HPCE)

form

solid

fluorescence

λ_ex 391 nm; λ_em 472 nm in methanol: 2-mercaptoethanol

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

CCN(CC)c1ccc2C(C)=C(C(=O)Oc2c1)c3ccc(cc3)N4C(=O)C=CC4=O

InChI

1S/C24H22N2O4/c1-4-25(5-2)18-10-11-19-15(3)23(24(29)30-20(19)14-18)16-6-8-17(9-7-16)26-21(27)12-13-22(26)28/h6-14H,4-5H2,1-3H3

InChI key

YGIABALXNBVHBX-UHFFFAOYSA-N

说明

Application

完整细胞的谷胱甘肽荧光探针；具体优点：只有硫代衍生物荧光，高量子产率和良好的斯托克斯位移

Biochem/physiol Actions

用于监测硫醇的释放，定量微孔板反应中的硫醇，并通过核仁蛋白染色区分增殖的癌细胞。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

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D J Steenkamp

The Biochemical journal, 292 ( Pt 1), 295-301 (1993-05-15)

Methods for the qualitative and quantitative analysis of thiols by means of the fluorogenic reagent 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin are described, with particular reference to the trypanosomatid metabolites glutathionylspermidine (GSH-spermidine) and trypanothione. Second-order rate constants for the derivatization of seven different thiols under

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