C2105
Z-Val-Ala-Asp氟甲基酮
≥90% (TLC), Caspase-1 inhibitor, powder
别名:
Z-VAD-FMK，未甲基化
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关于此项目
经验公式（希尔记法）:
C21H28FN3O7
化学文摘社编号:
分子量:
453.46
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
Z-Val-Ala-Asp氟甲基酮, powder, ≥90% (TLC)
Quality Level
assay
≥90% (TLC)
form
powder
shipped in
dry ice
storage temp.
−20°C
SMILES string
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF
InChI
1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1
InChI key
SUUHZYLYARUNIA-YEWWUXTCSA-N
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Teruyuki Kajiume et al.
Cell death discovery, 4, 111-111 (2018-12-12)
Mature neutrophils must be quickly removed from inflammatory sites to prevent tissue damage. Neutrophil removal is thought to be accomplished primarily through caspase-dependent apoptosis, which involves several genes of mitochondrial origin. However, mature neutrophils show reduced gene transcription and mitochondrial
Feng Shi et al.
Theranostics, 9(9), 2424-2438 (2019-05-28)
EBV infection is a recognized epigenetic driver of carcinogenesis. We previously showed that EBV could protect cancer cells from TNF-induced necroptosis. This study aims to explore the epigenetic mechanisms allowing cancer cells with EBV infection to escape from RIP3-dependent necroptosis.
Shuiping Liu et al.
Signal transduction and targeted therapy, 4, 53-53 (2019-12-10)
5-Fluorouracil (5-FU) is known as a first-line chemotherapeutic agent against colorectal cancer (CRC), but drug resistance occurs frequently and significantly limits its clinical success. Our previous study showed that the protocadherin 17 (PCDH17) gene was frequently methylated and functioned as
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| C2105-3MG | 04061833269602 |