T4661
Trizma ® 碱
≥99.9% (titration), crystalline
别名:
2-氨基-2-(羟甲基)-1,3-丙二醇, THAM, Tris 碱, 三羟甲基氨基甲烷, 氨基丁三醇
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关于此项目
线性分子式:
NH2C(CH2OH)3
化学文摘社编号:
分子量:
121.14
UNSPSC Code:
12352104
NACRES:
NA.25
PubChem Substance ID:
EC Number:
201-064-4
Beilstein/REAXYS Number:
741883
MDL number:
description
aminopeptidase substrate
Quality Level
assay
≥99.9% (titration)
form
crystalline
loss
≤5% (loss on drying, 110 °C)
color
white
pH
10.0-11.5
useful pH range
7-9
pKa (25 °C)
8.1
bp
219-220 °C/10 mmHg (lit.)
mp
167-172 °C (lit.)
solubility
water: soluble (400 g plus 600 mL of water)
λ
(290nm < 0.05), in 5 mM Tris; DNA (40% (w/w))
application(s)
diagnostic assay manufacturing
SMILES string
NC(CO)(CO)CO
InChI
1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChI key
LENZDBCJOHFCAS-UHFFFAOYSA-N
General description
Tris是用于生物化学和分子生物学公认的基础标准品和缓冲液。它可以单独用作缓冲液或混合缓冲液配方的组分，如Tris-EDTA（TE）缓冲液、Tris-乙酸盐-EDTA（TAE）缓冲液、Tris-硼酸盐-EDTA（TBE）缓冲液等。 它具有高纯度、较稳定、相对不吸湿、并且具有高的当量。
Application
Tris base已被用于：
- 作为细胞破裂的裂解缓冲液的组分
- 制备用于PAGE（聚丙烯酰胺凝胶电泳）的TBE溶液
- 肽核酸（PNA）的双链复合物及其互补DNA序列的研究中（通过使用阴离子交换HPLC）
- 毛细管电色谱和生育酚和生育三烯酚的紫外分析中
Features and Benefits
Features:
- Qualified Raw Materials: Products that meet the stringent requirements of the Elevated Assurance Program, ensuring compliance with regulatory standards.
- Comprehensive Documentation: Includes essential documents such as certificates, impurity profiles, and declarations to support audits and risk assessments.
- M-Clarity™ Quality Attributes: Products are classified within the MQ300 quality segment or higher, demonstrating superior quality assurance. M-Clarity™ Program
- Confirmed Process Controls: Established processes that ensure consistency and reliability in manufacturing.
- Enhanced Change Notification: Timely updates on any changes to product specifications or processes, ensuring transparency and compliance.
- Freely Available Dossiers: Access to robust, ready-to-present product dossiers that include:
- Site quality assessment
- ISO 9001 certificate
- Detailed product specifications
- Relevant declarations/statements (e.g., animal origin content, BSE/TSE, nitrosamine)
- Regulatory Compliance: Helps you meet compliance standards effectively, reducing the risk of regulatory issues.
- Audit Readiness: Instills confidence during audits with comprehensive documentation and confirmed process controls, demonstrating your commitment to high-quality products.
- Operational Transparency: Supports supply chain transparency, allowing you to track and verify the quality of raw materials.
- Enhanced Support: Provides exceptional quality-related information and tailored assistance to meet your specific needs.
- Risk Mitigation: Facilitates thorough risk assessments with detailed documentation, helping you manage potential compliance challenges.
- Informed Decision-Making: Access to clear and comprehensive product information enables better decision-making and enhances operational efficiency.
Packaging
所有规格与 T1503 相同。在生物技术方面，用于诊断或制造。请咨询最小起订量。
Analysis Note
未经过热原测试。可提供包含批次特定信息的分析证书。
Other Notes
所有缓冲液的 pH 值都取决于温度和浓度。Tris 缓冲液，温度每降低 1°C，pH 值增加约 0.03 个单位，每稀释十倍 pH 值降低0.03-0.05 个单位。
对于精确的应用，使用经过精心校准的 pH 计和玻璃/甘汞组合电极。
对于精确的应用，使用经过精心校准的 pH 计和玻璃/甘汞组合电极。
Legal Information
M-CLARITY is a trademark of Merck KGaA, Darmstadt, Germany
Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T4661-100G | 04061835266302 |
| T4661-1KG | 04061835266319 |
| T4661-5KG | 04061837346590 |