biological source
human plasma
Quality Level
assay
≥95% (SDS-PAGE)
form
buffered aqueous solution
mol wt
17.38 kDa
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... APOA2(336)
General description
Forms dimers in aqueous solutions with an association constant of 5 × 104 M-1. The association is accompanied by an enhancement of ~35% in α-helical content.
Application
Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).
Biochem/physiol Actions
Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.
Physical form
Solution in 10 mM ammonium bicarbonate.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
高风险级别生物产品--人源产品
此项目有
商品
由于胆固醇是水不溶性分子,必须包装后才能在血浆中运输。包装胆固醇、胆固醇酯和甘油三酯以便运输的颗粒称为脂蛋白。
Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.
Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.
Cécile Voisset et al.
The Journal of biological chemistry, 280(9), 7793-7799 (2005-01-06)
The scavenger receptor class B type I (SR-BI) has recently been shown to interact with hepatitis C virus (HCV) envelope glycoprotein E2, suggesting that it might be involved at some step of HCV entry into host cells. However, due to
Effect of disulfide cleavage on the molecular weight of one of the major polypeptides of human serum high density lipoprotein.
A M. Scanu et al.
FEBS letters, 18(2), 305-307 (1971-11-01)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A0972-.5MG | 04061833415191 |
| A0972-1MG | 04061826731604 |