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A4330

4′-氨甲基三氧沙林 盐酸盐

DNA and RNA virus inactivator, powder

别名:

4＆＃8242;氨基甲基-4,5-＆＃8242;，8三甲基补骨脂 盐酸盐

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关于此项目

经验公式（希尔记法）:
C15H15NO3 · HCl
化学文摘社编号:
62442-61-9
分子量:
293.75
UNSPSC Code:
12352200
PubChem Substance ID:
24890846
NACRES:
NA.77
MDL number:
MFCD00134837
Form:
powder
Quality level:
200
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产品名称

4′-氨甲基三氧沙林 盐酸盐,

form

powder

Quality Level

200

solubility

H2O: 1 mg/mL, DMSO: 2 mg/mL

storage temp.

2-8°C

SMILES string

CC1=CC(=O)Oc2c(C)c3oc(C)c(CN)c3cc12

InChI

1S/C15H15NO3/c1-7-4-13(17)19-14-8(2)15-11(5-10(7)14)12(6-16)9(3)18-15/h4-5H,6,16H2,1-3H3

InChI key

WBIICVGYYRRURR-UHFFFAOYSA-N

Application

4'-盐酸氨甲基三氧沙林可灭活 DNA 和 RNA 病毒，包括 HIV-1。4'-盐酸氨甲基三氧沙林在紫外光照射下可与核酸共价结合。

Biochem/physiol Actions

4'-盐酸氨甲基三氧沙林用于通过核酸交联和紫外线照射灭活 DNA 和 RNA 病毒，包括 HIV-1。

Features and Benefits

这种化合物是细胞凋亡研究的特色产品。 点击此处 ，发现更多特色细胞凋亡产品。访问sigma.com/discover-bsm了解更多关于其他研究领域的生物活性小分子的信息。

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
099M4015V
029M4063V
088M4099V
13180418
028M4084V

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DNA损伤和修复

DNA损伤和修复机制对于维持DNA完整性至关重要。细胞DNA的损伤与突变、癌症发展等有关。

DNA Damage and Repair

DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.

Discover Bioactive Small Molecules for Cell Cycle

Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

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M A Reynolds et al.
Bioconjugate chemistry, 3(5), 366-374 (1992-09-11)
A method is reported for conjugating an analog of 4'-(aminomethyl)-4,5',8- trimethylpsoralen to methylphophonate oligonucleotides. This method enables the psoralen moiety to be coupled to the phosphonate backbone between any two desired bases in a sequence. When hybridized to a target
A A Oroskar et al.
Free radical biology & medicine, 20(5), 751-756 (1996-01-01)
The ability of scavengers of hydroxyl radical (OH radical) to modulate the photosensitized relaxation (induction of the first single-strand break) of supercoiled plasmid DNA with UVA photoactivated 4'-aminomethyl-4,5',8-trimethylpsoralen was examined by comparing the dose reduction factor (DRF: the ratio of
S J Wagner et al.
Photochemistry and photobiology, 57(5), 819-824 (1993-05-01)
Psoralens and UVA light have been used in the laboratory to study the inactivation of viruses that may be infrequently present in platelet concentrates that are prepared for transfusion. In order to evaluate safety aspects of the treatment of platelet
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全球贸易项目编号

货号GTIN
A4330-5MG04061833368718