Merck
CN

A8412

Sigma-Aldrich

白蛋白 溶液 来源于牛血清

7.5% in DPBS, sterile-filtered, BioXtra, suitable for cell culture

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别名:
BSA溶液
CAS号:
MDL编号:
NACRES:
NA.75

生物来源

bovine

描述

low endotoxin

无菌性

sterile-filtered

产品线

BioXtra

检测方案

7.0-8.0% protein basis (UV)

形式

liquid

分子量

66.4 kDa

纯化方式

cold ethanol and heatshock fractionation

来源

USA origin

浓度

7.5% in DPBS

技术

cell culture | mammalian: suitable

杂质

≤13.0 EU/mL Endotoxin level

pH值(酸碱度)

6.5-7.5

异质活性

Mycoplasma test (Negative)
cell growth >50%

运输

ambient

储存温度

2-8°C

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一般描述

BSA是由约583个氨基酸残基组成,不含碳水化合物的单一多肽链。在pH 5-7时,它含有17个链内二硫键和1个巯基。

生化/生理作用

牛血清白蛋白被广泛用作细胞培养基,特别是无血清培养基(SFM)的添加剂。 它可带来一系列的好处,包括防止氧化损伤和稳定其他培养基成分,如脂肪酸和吡哆醛。

相关产品

产品编号
说明
价格

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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John R Horton et al.
Journal of medicinal chemistry, 61(7), 3193-3208 (2018-03-15)
Isomers of chiral drugs can exhibit marked differences in biological activities. We studied the binding and inhibitory activities of 12 compounds against KDM5A. Among them are two pairs of enantiomers representing two distinct inhibitor chemotypes, namely, ( R)- and (
William C Hines et al.
Breast cancer research and treatment, 155(1), 37-52 (2015-12-15)
Despite the prevalence and significant morbidity resulting from estrogen receptor positive (ER(+)) breast adenocarcinomas, there are only a few models of this cancer subtype available for drug development and arguably none for studying etiology. Those models that do exist have
Amanda J Shapiro et al.
Veterinary microbiology, 177(1-2), 154-161 (2015-03-18)
The seroprevalence of Coxiella burnetii (C. burnetii) in cats in eastern Australia is unknown, and the risk of transmission from cats to humans is undetermined. This study aimed to determine the exposure of cats to C. burnetii in four distinct
Paul J Orchard et al.
Scientific reports, 9(1), 7858-7858 (2019-05-28)
Cerebral adrenoleukodystrophy (cALD) is an inflammatory neurodegenerative disease associated with mutation of the ABCD1 gene. Proteomic analysis of cerebral spinal fluid (CSF) from young males with active cALD revealed markers of inflammation including APOE4. APOE4 genotype has been associated with
Pinar Sahin et al.
Fertility and sterility, 102(5), 1482-1490 (2014-09-23)
To evaluate the expression of mammalian target of rapamycin (mTOR) pathway molecules in mouse spermatogenesis and as well as its role during proliferation and meiotic initiation of spermatogenic cells. Experimental animal study. University. C57Balb-C adult male mice. Expressions of mTOR

商品

本页将全面阐述血清白蛋白和其他重要细胞培养成分如何影响用于单克隆抗体等外源蛋白生物制造的无血清细胞培养系统的性能,并介绍白蛋白的体外化学和生物化学过程。本页面将介绍白蛋白在体外化学和生物化学领域的应用。这些深度知识可能也适用于离体和组织工程学应用。

This page segues to comprehensive insights on how serum albumin and other important cell culture components affect the performance of serum-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of albumin. These insights may also be applied to ex vivo and tissue engineering applications.

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