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Merck
CN

C7039

Cefotaxime sodium salt 钠盐

powder or crystals, suitable for plant cell culture, BioReagent

别名:

Cefotaxim sodium salt 钠盐

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关于此项目

经验公式(希尔记法):
C16H16N5NaO7S2
化学文摘社编号:
分子量:
477.45
NACRES:
NA.72
PubChem Substance ID:
UNSPSC Code:
10171502
EC Number:
264-915-9
MDL number:
Beilstein/REAXYS Number:
5711411
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产品名称

Cefotaxime sodium salt 钠盐, suitable for plant cell culture, BioReagent, powder or crystals

product line

BioReagent

Quality Level

form

powder or crystals

technique(s)

cell culture | plant: suitable

color

off-white to pale yellow

solubility

H2O: 10% ( )

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

application(s)

agriculture

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

SMILES string

[Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O

InChI

1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1

InChI key

AZZMGZXNTDTSME-JUZDKLSSSA-M

General description

Chemical structure: β-lactam

Application

Cefotaxime sodium salt has been used as an test antibiotic in antibiotic susceptibility testing (AST) methods. It has also been used as an antibiotic to remove bacteria from O. tauri cultures.

Biochem/physiol Actions

Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria. It also has an ability to inhibit the cell division of lower plant organelles/plastids such as the photosynthetic organelles of glaucophytes and chloroplasts of bryophytes.
Mode of Action: Inhibits bacterial cell wall synthesis.
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Other Notes

Broad spectrum third generation cephalosporin antibiotic.
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

涉药品监管产品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

Reference guide and preparation guide for antibiotic and antimycotic use in plant tissue culture.


Valeria Di Dato et al.
Scientific reports, 9(1), 9893-9893 (2019-07-11)
Diatoms are phytoplankton eukaryotic microalgae that are widely distributed in the world's oceans and are responsible for 20-25% of total carbon fixation on the planet. Using transcriptome sequencing here we show for the first time that the ubiquitous diatom Thalassiosira
Urinary Tract Infection in Children and Antimicrobial Resistance Pattern: Children UTI and Antibiotic Resistance (2019)
Metabolic profiling identifies trehalose as an abundant and diurnally fluctuating metabolite in the microalga Ostreococcus tauri
Hirth M, et al.
Metabolomics, 13(9), 68-68 (2017)



全球贸易项目编号

货号GTIN
C7039-100MG04061835568284
C7039-1G04061835509621
C7039-10G04061835568291
C7039-500MG04061835568307
C7039-5G04061835568314