G1660
Galanthamine hydrobromide
From plant (Ungeria victoris), ≥94% (HPLC), Cholinesterase inhibitor, powder
别名:
Galantamine hydrobromide
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关于此项目
经验公式（希尔记法）:
C17H21NO3 · HBr
化学文摘社编号:
分子量:
368.27
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.32
EC Number:
217-780-5
MDL number:
产品名称
Galanthamine hydrobromide from Lycoris sp., ≥94% (HPLC)
biological source
plant (Ungeria victoris)
Quality Level
assay
≥94% (HPLC)
form
powder
mp
270 °C
solubility
DMSO: soluble 10 mg/mL, clear, colorless, water: soluble 20 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
Br[H].COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24
InChI
1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1
InChI key
QORVDGQLPPAFRS-XPSHAMGMSA-N
Gene Information
human ... ACHE(43)
General description
Galanthamine hydrobromide is a derivative of galanthamine, which is an anticholinestrase alkaloid derived from genus Lycoris (Amaryllidaceae) or snowdrop. This compound is used for the treatment of Alzheimer′s disease (AD).
Application
Galanthamine hydrobromide from Lycoris sp. has been used-
- as an AChE (acetylcholinesterase) inhibitor and positive control in acetylcholinesterase assay performed to determine the activity of AChE
- as a positive control in the screening of AChE inhibitors
- as a positive control in AChE inhibitory assay performed to determine the AChE-inhibitory activities of pyrithione and related sulfur-containing pyridine N-oxides
Biochem/physiol Actions
Cholinesterase inhibitor; reverses scopolamine-induced amnesia; antimyasthenic.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
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