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Merck
CN

HT501640

甲醛溶液,中性缓冲,10%

histological tissue fixative

别名:

甲醛

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关于此项目

UNSPSC Code:
12352114
PubChem Substance ID:
NACRES:
NA.47
MDL number:
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Quality Level

concentration

10% formalin (approx. 4% formaldehyde)

color

colorless

pH

6.90-7.10

density

1.080 g/cm3

application(s)

hematology
histology

storage temp.

room temp

SMILES string

[O-]#[C+H2]

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

General description

10%福尔马林中性缓冲液通常用作已被用作光学显微镜的固定剂。它需要相对较短的固定时间。它适用于长期储存组织。一旦被正确固定后,组织应该可以承受后续的组织处理或染色阶段。10% NBF很适合于高通量的实验室,并只需要一段相对短的固定时间,但也可用于组织的长期储存。福尔马林通过让蛋白质分子交联形成凝胶而固定,使细胞保持生活状态时的形态结构。

Application

10%中性福尔马林溶液是备受欢迎的通用组织学固定剂。通过防止组织腐败、维持其分子结构来保存组织样本。
常用的通用组织学固定剂。

Biochem/physiol Actions

Formaldehyde is both a non-coagulant and an additive fixative. Formalin fixation is thought to form cross links between the aldehydes and the proteins, creating a gel, thus retaining cellular constituents in their in vivo relationship. Formaldehyde is known to penetrate tissue quickly, but the fixation process may take a long time to form the various cross links with tissue proteins.

Features and Benefits

  • 10% NBF is well-suited for large throughput laboratories.
  • It requires a relatively short period of fixation.
  • It can be used for the long-term storage of tissue.

Packaging

产品包装在一个 20L 的软方桶中,由纸板箱内的塑料气囊和连接的插口组成。

Physical form

中性缓冲的溶液


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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Skin Sens. 1

wgk

WGK 3

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

185.0 °F

flash_point_c

85 °C



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Autophagy in Dendritic Cells and B Cells Is Critical for the Inflammatory State of TLR7-Mediated Autoimmunity.
Weindel C G, et al.
Journal of Immunology, 198, 1081-1092 (2016)
Fan Liu et al.
Journal of biomaterials applications, 33(9), 1168-1177 (2019-01-23)
To investigate the osteogenesis of macro-pore sized bone scaffolds, biphasic calcium phosphate scaffolds with accurately controlled macro-pore size (0.8, 1.2, and 1.6 mm) and identical porosity of 70% were fabricated by the 3D printing technology. Eight New Zealand rabbits were
B cell autophagy mediates TLR7-dependent autoimmunity and inflammation.
Weindel C G, et al
Autophagy, 11(5), 1010-1024 (2015)



全球贸易项目编号

货号GTIN
HT501640-19L04061833835449