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Merck
CN

K7125

(±)-3-甲基-2-氧戊酸 钠盐

别名:

(±)-3-甲基-2-氧代戊酸钠, 3-甲基-2-氧基戊酸 钠盐, DL-α-酮基-β-甲基戊酸 钠盐, 酮异亮氨酸 钠盐

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关于此项目

线性分子式:
CH3CH2CH(CH3)COCOONa
化学文摘社编号:
分子量:
152.12
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
266-503-4
Beilstein/REAXYS Number:
7779663
MDL number:
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Quality Level

lipid type

saturated FAs

storage temp.

2-8°C

SMILES string

[Na+].CCC(C)C(=O)C([O-])=O

InChI

1S/C6H10O3.Na/c1-3-4(2)5(7)6(8)9;/h4H,3H2,1-2H3,(H,8,9);/q;+1/p-1

InChI key

SMDJDLCNOXJGKC-UHFFFAOYSA-M

Biochem/physiol Actions

(±)-3-甲基-2-氧戊酸钠盐是 D-和 L-3-甲基-2-氧戊酸的混合物。以 3-甲基-2-氧代戊酸为底物,研究 α-酮酸脱氢酶类。α-酮-β-甲基戊酸用于抑制线粒体 α——酮戊二酸脱氢酶复合物 (KGDHC) 诱导和研究神经细胞死亡。α-酮-β-甲基戊酸可作为活性氧清除剂进行研究。


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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F Lahnsteiner
Journal of fish biology, 75(4), 816-833 (2010-08-27)
The present study investigated (1) the free amino acid (FAA) composition in semen of rainbow trout Oncorhynchus mykiss and carp Cyprinus carpio, (2) enzyme systems involved in amino acid metabolism and (3) the effect of amino acids on sperm viability
Cláudia Funchal et al.
Journal of the neurological sciences, 260(1-2), 87-94 (2007-05-15)
Accumulation of the branched-chain alpha-keto acids (BCKA), alpha-ketoisocaproic acid (KIC), alpha-keto-beta-methylvaleric acid (KMV) and alpha-ketoisovaleric acid (KIV) and their respective branched-chain alpha-amino acids (BCAA) occurs in tissues and biological fluids of patients affected by the neurometabolic disorder maple syrup urine
Hsueh-Meei Huang et al.
Biochimica et biophysica acta, 1637(1), 119-126 (2003-01-16)
Mitochondrial dysfunction occurs in many neurodegenerative diseases. The alpha-ketoglutarate dehydrogenase complex (KGDHC) catalyzes a key and arguably rate-limiting step of the tricarboxylic acid cycle (TCA). A reduction in the activity of the KGDHC occurs in brains and cells of patients



全球贸易项目编号

货号GTIN
K7125-5G04061833944783