form
lyophilized powder
Quality Level
potency
<0.1 μg per mL agglutination activity
quality
Affinity-purified
impurities
salt, free
storage temp.
−20°C
General description
从 Arachis hypogaea (花生)中提取的凝集素是分子量 110 kDa的同四聚体蛋白。
Application
从 Arachis hypogaea (花生)中提取的凝集素用于:
- 检测 Thomson-Friedenreich 抗原
- 作为PBS的成分,研究其对细胞活力的影响
- 研究其阻断结合位点的能力
Biochem/physiol Actions
从Arachis hypogaea (花生)中提取的凝集素对 Thomson − Friedenreich 抗原的 β -D-Gal(1-3)-D-galNAc 残基具有特异性。 在许多鳞状细胞癌诊断和预后中,是最广泛使用的标志物。
花生凝集素不会凝集正常的人类红细胞,但会强烈凝集神经氨酸酶处理的红细胞。花生凝集素具有与人血清中的抗 T 抗体相似的有效抗 T 活性。凝集素可用于区分人淋巴细胞亚群。
Analysis Note
凝集活性以 μg/ml 表示,并根据 1 mg/mL 溶液在磷酸盐缓冲盐水 (pH 6.8) 中的系列稀释液测定。该活性是在 25°C 下孵育 1 h 后凝集 2% 神经氨酸酶处理的人 O 型红细胞悬液的最低浓度。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
Expression of peanut agglutinin-binding mucin-type glycoprotein in human esophageal squamous cell carcinoma as a marker
Kannan S, et al.
Molecular Cancer, 2(1), 38-38 (2003)
Peter Gassmann et al.
BMC cancer, 10, 177-177 (2010-05-04)
Metastasis formation is the leading cause of death among colon cancer patients. We established a new in-situ model of in vivo microscopy of the lung to analyse initiating events of metastatic tumor cell adhesion within this typical metastatic target of
Lectin binding and effects in culture on human cancer and non-cancer cell lines: examination of issues of interest in drug design strategies
Petrossian K, et al.
Acta Histochemica, 109(6), 491-500 (2007)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| L0881-10MG | 04061833263006 |
| L0881-25MG | 04061833949054 |
| L0881-5MG | 04061833949061 |