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M8146

Methyl-β-D-thiogalactoside

Name: Methyl-β-<SC>D</SC>-thiogalactoside
Brand: SIGMA

别名:

Methyl-1-thio-β-D-galactopyranoside, TMG

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关于此项目

经验公式（希尔记法）:

C₇H₁₄O₅S

化学文摘社编号:

155-30-6

分子量:

210.25

UNSPSC Code:

12352201

NACRES:

NA.25

PubChem Substance ID:

24897226

EC Number:

205-842-4

Beilstein/REAXYS Number:

81583

MDL number:

MFCD00038073

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属性

biological source

synthetic

Quality Level

200

assay

≥98% (TLC)

form

powder

technique(s)

thin layer chromatography (TLC): suitable

color

white

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CS[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C7H14O5S/c1-13-7-6(11)5(10)4(9)3(2-8)12-7/h3-11H,2H2,1H3/t3-,4+,5+,6-,7+/m1/s1

InChI key

LZFNFLTVAMOOPJ-PZRMXXKTSA-N

说明

General description

The uptake of methyl-β-D-thiogalactoside (TMG), lactose, and glucose is maintained by the phosphoenolpyruvate-dependent phosphotransferase system.

Application

Methyl-β-D-thiogalactoside has been used in a study to analyze inducers of the E.coli lac repressor system. It has also been used in a study that investigated the utilization of lactose by Streptococcus faecalis.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Analysis of inducers of the E.coli lac repressor system in mammalian cells and whole animals.

D L Wyborski et al.

Nucleic acids research, 19(17), 4647-4653 (1991-09-11)

Although the inducible prokaryotic lac repressor system has been successfully adapted for control of gene expression in mammalian cells, little information is available on the pharmacokinetics of beta-galactoside inducers in mammalian cells for optimizing this system. These studies directly measure

Arginine binding motifs: design and synthesis of galactose-derived arginine tweezers as galectin-3 inhibitors.

Christopher T Oberg et al.

Journal of medicinal chemistry, 51(7), 2297-2301 (2008-03-06)

Anionic O2 derivatives of methyl 3-deoxy-3-(4-methylbenzamido)-1-thio-beta-D-galactopyranoside have been synthesized as inhibitors against galectin-3. The sulfate, H-phosphonate, and benzyl phosphate derivatives showed an increased affinity as compared to the parent unsubstituted galactopyranoside. Modeling revealed arginine-144 being pinched by the C3 benzamide

β-D-phosphogalactoside galactohydrolase of Streptococcus faecalis and the inhibition of its synthesis by glucose

Heller, K. and R. Roschenthaler

Canadian Journal of Microbiology, 24, 512-519 (1979)

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全球贸易项目编号

货号	GTIN
M8146-1G	04061826060896
M8146-250MG	04061834062837