O2136
油酸酰胺
≥99% (TLC), powder, sleep-inducing brain lipid
别名:
顺式-9,10-十八碳烯酰胺, 顺式-9-十八烯胺, 油酸酰胺
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关于此项目
经验公式（希尔记法）:
C18H35NO
化学文摘社编号:
分子量:
281.48
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
206-103-9
MDL number:
Assay:
≥99%
Quality level:
产品名称
油酸酰胺, ≥99%
Quality Level
assay
≥99%
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
storage temp.
−20°C
SMILES string
CCCCCCCC\C=C/CCCCCCCC(N)=O
InChI
1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-
InChI key
FATBGEAMYMYZAF-KTKRTIGZSA-N
General description
油酰胺是脂质或大脑脂肪酸，可在CSF（脑脊液）中找到。最初得自剥夺睡眠的猫的脑脊液。
Application
油酰胺已用作葡萄糖和半乳糖培养基中的补充剂，用于防止半乳糖诱导Leigh综合征。
Biochem/physiol Actions
油酰胺有促进睡眠的效果。它拥有多种属性，如大麻素类活性。油酰胺也可通过大鼠神经胶质细胞间隙连接阻断通信。
睡眠诱导脑脂质，其变构调节GABAA受体并增强5-HT7血清素受体反应。大鼠和人类CB1大麻素受体的选择性内源性激动剂。
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hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
404.6 °F - closed cup
flash_point_c
207 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
商品
Discover Bioactive Small Molecules for Lipid Signaling Research
Oleamide and anandamide effects on food intake and sexual behavior of rats
Martinez-Gonzalez D, et al.
Neuroscience Letters, 364(1), 1-6 (2004)
The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells
Guan X, et al.
The Journal of Cell Biology, 139(7), 1785-1792 (1997)
Gayong Shim et al.
Journal of controlled release : official journal of the Controlled Release Society, 155(1), 60-66 (2010-10-26)
Oligolysine-based cationic lipid derivatives were synthesized for delivery of siRNA, and formulated into cationic liposomes. Among various oligolysine-based lipid derivatives differing in lysine residue number and lipid moiety, trilysinoyl oleylamide (TLO)-based liposomes (TLOL) showed the highest delivery efficiency combined with
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| O2136-100MG | 04061834217862 |
| O2136-500MG | 04061833264546 |