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Merck
CN

P4747

Anti-Potassium Channel KCa2.3, (C-term) (Small-conductance Ca2+-activated Potassium Channel 3) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

别名:

Anti-SK3, Anti-SKCa3

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human, mouse, rat, pig

technique(s)

western blot: 1:200 using rat brain membranes

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KCNN3(3782)
mouse ... Kcnn3(140493)
rat ... Kcnn3(54263)

Immunogen

Synthetic peptide corresponding to amino acid residues 659-674 of human KCa2.3. This sequence has 100% homology in rat, mouse, pig.

Physical form

Lyophilized powder from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容


H Tomita et al.
Molecular psychiatry, 8(5), 524-535 (2003-06-17)
The small-conductance calcium-activated K(+) channel SK3 (SKCa3/KCNN3) regulates electrical excitability and neurotransmitter release in monoaminergic neurons, and has been implicated in schizophrenia, ataxia and anorexia nervosa. We have identified a novel SK3 transcript, SK3-1B that utilizes an alternative first exon
C Vergara et al.
Current opinion in neurobiology, 8(3), 321-329 (1998-08-04)
Calcium-activated potassium channels are fundamental regulators of neuronal excitability, participating in interspike interval and spike-frequency adaptation. For large-conductance calcium-activated potassium (BK) channels, recent experiments have illuminated the fundamental biophysical mechanisms of gating, demonstrating that BK channels are voltage gated and
Shaun L Sandow et al.
Journal of anatomy, 209(5), 689-698 (2006-10-26)
Activation of endothelial cell small- (S) and intermediate- (I) conductance calcium-activated potassium channels (K(Ca)) and current or molecular transfer via myoendothelial gap junctions underlies endothelium-derived hyperpolarization leading to vasodilation. The mechanism underlying the K(Ca) component of vasodilator activity and the



全球贸易项目编号

货号GTIN
P4747-200UL04061835752478