P6777
苯乙肼 硫酸盐
synthetic, ≥98% (iodine, titration), MAO-A/B inhibitor, powder
别名:
苯乙肼硫酸氢盐
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关于此项目
经验公式（希尔记法）:
C8H12N2 · H2O4S
化学文摘社编号:
分子量:
234.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
205-856-0
MDL number:
产品名称
苯乙肼 硫酸盐,
biological source
synthetic
Quality Level
assay
≥98% (iodine, titration)
form
powder
solubility
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
SMILES string
NNCCC1=CC=CC=C1.OS(=O)(O)=O
InChI
1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)
InChI key
RXBKMJIPNDOHFR-UHFFFAOYSA-N
Gene Information
human ... MAOA(4128), MAOB(4129)
Biochem/physiol Actions
非选择性 MAO-A/B 抑制剂。
Features and Benefits
该化合物收录于受体分类和信号转导手册的《多巴胺和去甲肾上腺素代谢》页面。想要浏览手册的其他页面， 请单击此处。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
商品
血清素（5-羟色胺）主要存在于三种主要细胞类型中：i）中杻神经系统（CNS）和肠肌间神经丛中的血清素能神经元，ii）胃肠道粘膜中的肠嗜铬细胞，和iii）血小板。血清素的代谢主要通过外部线粒体膜酶单胺氧化酶（MAO）进行，它以两种分子亚型存在，分别称为MAO-A和MAO-B。
Serotonin is stored in cells and metabolized by MAO, influencing CNS, GI, and platelet functions.
The effect of riluzole augmentation in a patient with treatment-resistant obsessive-compulsive disorder, taking two other glutaminergic agents.
Nahla Mahgoub et al.
The Journal of neuropsychiatry and clinical neurosciences, 23(2), E24-E25 (2011-06-17)
Darrick T Balu et al.
Brain research, 1211, 37-43 (2008-04-25)
Antidepressant treatments have been proposed to produce their therapeutic effects, in part, through increasing neurotrophin levels in the brain. The current experiments investigated the effects of acute and chronic treatment with different pharmacologic and somatic antidepressant treatments on protein levels
Anna Z Antosik-Wójcińska et al.
Psychiatria polska, 47(1), 127-134 (2013-07-31)
The use of non-selective monoamine oxidase inhibitors (IMAO) may be associated with the risk of addiction, which is confirmed by case studies published so far. Harmful use of antidepressants in patients with affective disorders and anxiety is not frequent, but
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P6777-25G | 04061832948478 |
| P6777-5G | 04061834394013 |