R1033
RN-1747
≥98% (HPLC)
别名:
1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine;, 1-[(4-Chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)-piperazine
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关于此项目
经验公式（希尔记法）:
C17H18ClN3O4S
化学文摘社编号:
分子量:
395.86
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
light yellow to light tan
solubility
DMSO: ≥10 mg/mL
storage temp.
2-8°C
SMILES string
[O-][N+](=O)c1cc(Cl)ccc1S(=O)(=O)N2CCN(CC2)Cc3ccccc3
InChI
1S/C17H18ClN3O4S/c18-15-6-7-17(16(12-15)21(22)23)26(24,25)20-10-8-19(9-11-20)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2
InChI key
ZNLVYSJQUMALEO-UHFFFAOYSA-N
Biochem/physiol Actions
TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands, hypotonicity, protein kinases and, possibly, mechanical inputs.
TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands, hypotonicity, protein kinases and, possibly, mechanical inputs. TRPV4 is a nociceptor playing an important role in inflammatory and neuropathic mechanical hyperalgesia in rodent models apparently specifically activated under pathological conditions.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
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Fructose-1,6-bisphosphate (FBP) aldolase links sensing of declining glucose availability to AMPK activation via the lysosomal pathway. However, how aldolase transmits lack of occupancy by FBP to AMPK activation remains unclear. Here, we show that FBP-unoccupied aldolase interacts with and inhibits
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| R1033-25MG | 04061832559490 |
| R1033-5MG | 04061832559506 |