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安全信息

R4251

Sigma-Aldrich

核糖核酸,转移 来源于大肠杆菌

Type XXI, Strain W, lyophilized powder

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别名:
tRNA, 转移RNA
CAS号:
MDL编号:

类型

Type XXI

形式

lyophilized powder

储存温度

−20°C

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应用

Ribonucleic acid, transfer from Escherichia coli, Type XXI, Strain W may be used as a starting material for the purification of specific amino acyl-tRNA species by methods such as liquid column chromatography or high-performance liquid chromatography (HPLC).

生化/生理作用

Transfer RNA is an amino acid acceptor in the reaction with Aminoacyl-tRNA Synthetase and various amino acids, resulting in the formation of aminoacyl-tRNA.

单位定义

一单位在 1.0mL 水(1cm 光程)中的 A260 为 1.0。

法规信息

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Jean Lehmann et al.
Nucleic acids research, 41(10), 5494-5502 (2013-04-13)
The structure and function of conserved motifs constituting the apex of Stem I in T-box mRNA leaders are investigated. We point out that this apex shares striking similarities with the L1 stalk (helices 76-78) of the ribosome. A sequence and
Manuel Neeb et al.
Journal of medicinal chemistry, 57(13), 5566-5578 (2014-06-25)
Lead optimization focuses on binding-affinity improvement. If a flat structure-activity relationship is detected, usually optimization strategies are abolished as unattractive. Nonetheless, as affinity is composed of an enthalpic and entropic contribution, factorization of both can unravel the complexity of a
Tanja Kalstrup et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(20), 8272-8277 (2013-05-01)
Atomic-scale models on the gating mechanism of voltage-gated potassium channels (Kv) are based on linear interpolations between static structures of their initial and final state derived from crystallography and molecular dynamics simulations, and, thus, lack dynamic structural information. The lack
Narayana Annaluru et al.
Science (New York, N.Y.), 344(6179), 55-58 (2014-03-29)
Rapid advances in DNA synthesis techniques have made it possible to engineer viruses, biochemical pathways and assemble bacterial genomes. Here, we report the synthesis of a functional 272,871-base pair designer eukaryotic chromosome, synIII, which is based on the 316,617-base pair
Stefan Klumpp et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(42), 16754-16759 (2013-10-02)
Bacterial growth is crucially dependent on protein synthesis and thus on the cellular abundance of ribosomes and related proteins. Here, we show that the slow diffusion of the bulky tRNA complexes in the crowded cytoplasm imposes a physical limit on

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