biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
69 kDa
species reactivity
mouse, human
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... IFI16(3428)
mouse ... Ifi204(15951)
Immunogen
Synthetic peptide directed towards the middle region of mouse Ifi204
Biochem/physiol Actions
Ifi204 inhibits the transcription of ribosomal RNA.Ifi204 may inhibit DNA binding by UBTF. Ifi204 inhibits cell growth via TP53/p53 and RB1-dependent and independent pathways.Ifi204 acts as a coactivator of RUNX2 during osteogenesis. Ifi204 may be involved in macrophage differentiation.Ifi204 enables skeletal muscle and cardiac myocyte differentiation by sequestring Id proteins in the cytosol and promoting their ubiquitination and subsequent degradation.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: EAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQARTSTAQAGT
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
常规特殊物品
此项目有
Mark N Lee et al.
Nature immunology, 14(2), 179-185 (2012-12-25)
The innate immune system senses viral DNA that enters mammalian cells, or in aberrant situations self-DNA, and triggers type I interferon production. Here we present an integrative approach that combines quantitative proteomics, genomics and small molecule perturbations to identify genes
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB2105265-100UL | 04061836121112 |
| SAB2105265-50UG | 04061832070957 |