biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 19 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... DDIT3(1649)
General description
CCAAT/增强子结合蛋白同源蛋白(CHOP)是一种转录调节因子, 位于人类染色体12q13上。 它也被称为DNA损伤诱导转录本3(DDIT3)。
抗-CHOP抗体可检测总CHOP蛋白的内源性水平。
Immunogen
针对人源 CHOP 的合成肽产生抗血清。
免疫原范围:15-64
免疫原范围:15-64
Application
抗CHOP N末端抗体已被用于蛋白提取和蛋白印迹中。
Biochem/physiol Actions
CCAAT/增强子结合蛋白同源蛋白(CHOP)控制内质网(ER)应激介导的细胞凋亡。它也调节细胞脂质代谢的转录。CHOP控制慢性肾脏病诱导的血管钙化。
Features and Benefits
您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果,我们将给予您完全的赔偿或更换抗体。 了解更多。
Physical form
兔IgG,溶于磷酸盐缓冲盐水(不含Mg2+和Ca2+),pH7.4,150mM NaCl,0.02%叠氮化钠和50%甘油中。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Sujata Saraswat Ohri et al.
Journal of neurotrauma, 29(3), 579-588 (2011-09-22)
Manipulation of various components of the endoplasmic reticulum (ER) stress response (ERSR) has led to functional recovery in diabetes, cancer, and several neurodegenerative diseases, indicating its use as a potential therapeutic intervention. One of the downstream pro-apoptotic transcription factors activated
C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis
Rahman K, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 96(8), 895-908 (2016)
Endoplasmic reticulum stress effector CCAAT/enhancer-binding protein homologous protein (CHOP) regulates chronic kidney disease-induced vascular calcification
Miyazaki-Anzai S, et al.
Journal of the American Heart Association (2014)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB4500631-100UG | 04061837744099 |