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Merck
CN

SAB4501145

Anti-LATS1 antibody produced in rabbit

affinity isolated antibody

别名:

Kinase phosphorylated during mitosis protein, Large tumor suppressor homolog 1, Serine/threonine-protein kinase kpm, WARTS protein kinase, h-warts/ Large tumor suppressor homolog 2

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC
Citations:
3
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 126 kDa

species reactivity

human, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:40000, immunohistochemistry: 1:50-1:100

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LATS1(9113)

General description

Anti-LATS1 Antibody detects endogenous levels of total LATS1 protein.
The LATS1 (large tumor suppressor kinase 1) gene encodes a serine/threonine kinase and is located on human chromosome 6q24-25. It is present in the mitotic apparatus. It is also called as WARTS.

Immunogen

The antiserum was produced against synthesized peptide derived from human LATS1/2.

Immunogen Range: 1041-1090

Biochem/physiol Actions

The LATS1 (large tumor suppressor kinase 1) protein repress the multiplication and invasion of cervical cancer. It acts as a cell cycle inhibitor. Low level expression of LATS1 is associated with the progression and prognosis of glioma. It is a tumor suppressor gene, thereby it participates in various mitotic processes.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
低风险生物材料

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Decreased expression of LATS1 is correlated with the progression and prognosis of glioma
Ji T, et al.
Journal of Experimental & Clinical Cancer Research (2012)
Underexpression of LATS1 TSG in colorectal cancer is associated with promoter hypermethylation
Wierzbicki PM, et al.
World Journal of Gastroenterology, 19(27), 4363-4373 (2013)
LATS1 suppresses proliferation and invasion of cervical cancer
Deng J, et al.
Molecular Medicine Reports, 15(4), 1654-1660 (2017)



全球贸易项目编号

货号GTIN
SAB4501145-100UG04061837185441