Biochem/physiol Actions
Neuromedin N is a hexapeptide that is related to neurotensin. Its precursor, proneuromedin N, is expressed in the adrenals, brain, gut and also in several cancers. In myoelectric activity, it has been reported to act in a similar manner as neurotensin, at a lesser degree of potency. Neuromedin N has been shown to increase the chemotaxis capacity of mouse lymphocytes and to modulate function of the hypothalamo-pituitary-adrenocortical axis in rats. Neuromedin N has been proposed to exert its actions via increase in intracellular Ca2+ concentration, although this is uncertain.
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11 - Combustible Solids
wgk
WGK 3
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Not applicable
flash_point_c
Not applicable
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Investigation of proNT/NMN secretion from small cell lung carcinoma cells using a mouse xenograft model.
Wakabayashi-Nakao K
Oncology Reports, 28(4), 1181-1186 (2012)
I Schultz et al.
Regulatory peptides, 35(3), 197-205 (1991-09-03)
The effects of neuromedin-N on migrating myoelectric complexes in the small intestine of rats were studied. As neuromedin-N and neurotensin are structurally related peptides a comparison with neurotensin was made. Myoelectric activity was recorded by means of three bipolar electrodes
M De la Fuente et al.
Journal of neuroimmunology, 42(1), 97-104 (1993-01-01)
The neuropeptides neurotensin and neuromedin N (from 10(-12) M to 10(-9) M) have been shown in this study to stimulate significantly in vitro several steps of the phagocytic process: adherence to substrate, chemotaxis, ingestion of inert particles (latex beads) and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SCP0200-10MG | 04061833025369 |