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Merck
CN

SRE0066

盐酸胍溶液,6M

别名:

盐酸氨基甲脒, 盐酸胍, 胍盐酸盐

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变更视图

关于此项目

NACRES:
NA.25
UNSPSC Code:
12352209
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form

liquid

Quality Level

concentration

6 M

impurities

<100 cfu/mL Bioburden

color

colorless

pH

4.5—5.5

density

1.1 —1.3  g/cm3

application(s)

diagnostic assay manufacturing

storage temp.

room temp

Application

盐酸胍常用作变性剂,因为它能使氨基酸残基间氢键断裂。通过断开这些键,蛋白质的 3D 构象被展开,蛋白质的水溶性大大增加。一旦变性,可通过各种程序轻松还原、修饰或分析蛋白质。样品的进一步处理可以使蛋白质通过其他常见的蛋白质分析方法进行分析,包括质谱、电泳和酶消化。
盐酸胍通常也用于 RNA 的分离、球状蛋白质的变性和蛋白质复性研究。也可用于促进胰蛋白酶肽的生成,用于复杂蛋白样品的分析。

Physical form

本品为即用型 6 M 盐酸胍溶液。6 M 盐酸胍溶液可用作储备液,制备以下溶液: 适当降低浓度。

注:如果 6 M 缓冲液中存在沉淀,则将瓶加热至 37°C,混合直至完全溶解后使用。


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

A complete workflow for the intact and middle-up mass analysis of reduced and non-reduced monoclonal antibodies based on SEC-MS with sample preparation by protein-A affinity clean-up.

SEC-MS protocol for rapid glycoprofiling of monoclonal antibodies with antibody purification and mass spectrometer calibration.

商品

A complete reversed phase HPLC-ELSD workflow, including sample preparation for the analysis of Polysorbate 80 in a monoclonal antibody formulation.

A RPLC-MS workflow for mass analysis of non-reduced monoclonal antibody, trastuzumab, including calibration, and system suitability tests.

A RPLC-MS workflow for mass analysis of reduced monoclonal antibody, trastuzumab, including reduction procedures, calibration, and system suitability tests.


Kaamini M Dhanabalan et al.
Biomaterials science, 8(15), 4308-4321 (2020-07-01)
Osteoarthritis (OA) is a joint disease characterized by progressive damage of articular cartilage and the adjoining subchondral bone. Chondrocytes, the primary cells of the cartilage, have limited regenerative capacity and when they undergo stress due to trauma or with aging
Yoshinori Aso et al.
eLife, 8 (2019-11-15)
Animals employ diverse learning rules and synaptic plasticity dynamics to record temporal and statistical information about the world. However, the molecular mechanisms underlying this diversity are poorly understood. The anatomically defined compartments of the insect mushroom body function as parallel



全球贸易项目编号

货号GTIN
SRE0066-4L04061838175427
SRE0066-100ML04061838074188
SRE0066-500ML04061838101228