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关于此项目
化学文摘社编号:
UNSPSC Code:
12352202
EC Number:
234-318-8
NACRES:
NA.83
MDL number:
eCl@ss:
34058011
Form:
powder
Assay:
≥98%
Biological source:
bovine
biological source
bovine
Quality Level
product line
BioReagent
assay
≥98%
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
iron, essentially free
solubility
H2O: 10 mg/mL
UniProt accession no.
storage temp.
2-8°C
Gene Information
bovine ... TF(280705)
General description
脱铁转铁蛋白是一种无铁形式的转铁蛋白,存在于循环系统中。
Application
所有细胞都需要铁才能从其环境中适当吸收氧气。 转铁蛋白是一种从血清中分离出来的蛋白质,可引起铁从培养基中摄取并转运到细胞中。 这允许适当的氧气吸收,并且还刺激与生长相关的酶活性。 铁饱和转铁蛋白(全转铁蛋白)在释放铁后不断循环,变成缺铁转铁蛋白(脱辅基转铁蛋白)。 选择使用哪种形式取决于培养条件。 在诸如含有高水平铁盐的Dulbecco′s改良的Eagle′s培养基/Ham′s营养混合物F12(DMEM/F12)的培养基中,优选使用脱铁转铁蛋白。
牛载脂蛋白转铁蛋白已用作以下材料的组分:
- 牛乳腺上皮细胞培养的基础培养基
- 精原干细胞培养的最低必需培养基α(MEM-α)
- 间充质干细胞培养的诱导培养基
Biochem/physiol Actions
脱铁转铁蛋白(apoTf)有助于防止铁在组织中积聚,特别是在非输血依赖型β地中海贫血中。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
此项目有
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