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Merck
CN

X2628

光溜海绵素C

IP3 receptor Inhibitor, film

别名:

XeC

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关于此项目

线性分子式:
C28 H50 N2 O2
化学文摘社编号:
分子量:
446.71
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
film
Quality level:
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产品名称

光溜海绵素C, film

form

film

Quality Level

color

colorless

solubility

DMSO: soluble

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@]12CCCCCC[C@@]3([H])CCCN4CC[C@@]([H])(CCCCCC[C@]5([H])CCCN(CC1)[C@@]5([H])O2)O[C@@]34[H]

InChI

1S/C28H50N2O2/c1-3-7-15-25-17-21-30-20-10-14-24(28(30)31-25)12-6-2-4-8-16-26-18-22-29-19-9-13-23(11-5-1)27(29)32-26/h23-28H,1-22H2/t23-,24+,25-,26-,27+,28+/m1/s1

InChI key

PQYOPBRFUUEHRC-HCKQMYSWSA-N

General description

从 Okanowan 海洋海绵中分离得到的大环双-1-氧喹啉脒的合成形式。

Biochem/physiol Actions

Xestospongin C 是 IP 3 介导的 Ca 2 + 释放 (IC 50 = 358 nM) 的强效、可逆和膜渗透性阻断剂。
Xestospongin C 是 IP 3 受体的选择性、可逆性和膜通透性抑制剂。可逆地阻断缓激肽-和氨甲酰胆碱-Ca 2 + 从内质网储存中流出。

Features and Benefits

《受体分类和信号转导》手册的 InsP3/Ryanodine 受体页有该化合物的介绍。想要浏览手册的其他页面, 请单击此处

Packaging

氮气中包装,密封。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
X2628-10UG04061837545474
X2628-50UG04061833632710