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Merck
CN

V900919

两性霉素B 来源于链霉菌

suitable for cell culture, Vetec, BioReagent

别名:

两性霉素B 来源于链霉菌 属, Fungizone

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关于此项目

经验公式(希尔记法):
C47H73NO17
化学文摘社编号:
分子量:
924.08
UNSPSC Code:
12352207
PubChem Substance ID:
EC Number:
215-742-2
Beilstein/REAXYS Number:
78342
MDL number:
eCl@ss:
34010400
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产品名称

两性霉素B 来源于链霉菌 属, Vetec, reagent grade, BioReagent, suitable for cell culture, ~80%

grade

reagent grade

Quality Level

product line

BioReagent, Vetec

assay

~80%

technique(s)

cell culture | mammalian: suitable

antibiotic activity spectrum

fungi, yeast

mode of action

cell membrane | interferes

shipped in

wet ice

storage temp.

2-8°C

SMILES string

C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\2)C[C@H](O)[C@H]3C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O

InChI

1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1

InChI key

APKFDSVGJQXUKY-INPOYWNPSA-N

Biochem/physiol Actions

两性霉素B可用于急性侵袭性真菌感染的初级治疗,例如曲霉菌病。
两性霉素B可与甾醇结合,在膜中形成孔,并导致小分子的泄漏。该产品对真菌和酵母最有效。

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

STOT RE 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis.
Herbrecht R, et al.
The New England Journal of Medicine, 347(6), 408-415 (2002)
Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia.
White MH, et al.
Clinical Infectious Diseases, 27(2), 296-302 (1998)
Malav S Trivedi et al.
The Journal of nutritional biochemistry, 25(10), 1011-1018 (2014-07-16)
Dietary interventions like gluten-free and casein-free diets have been reported to improve intestinal, autoimmune and neurological symptoms in patients with a variety of conditions; however, the underlying mechanism of benefit for such diets remains unclear. Epigenetic programming, including CpG methylation



全球贸易项目编号

货号GTIN
V900919-1G04061826759004