EGFR
epidermal growth factor receptor
Synonyms:
ERBB, ERBB1, HER1, PIG61, mENA
Species:
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), fruit fly Egfr (37455), cow EGFR (407217), Horse EGFR (100067755), domestic cat EGFR (100510799), dog EGFR (404306), chicken EGFR (396494), domestic guinea pig Egfr (100725363) ...More
UniProtKB ID:
Gene ID:
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
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Custom Gene Products
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ELISA
Product Number
Description
Species
Phospho-EGFR (pTyr1068) ELISA Kit, for detection of human phospho-egfr (pTyr1068) in cell and tissue lysates,
Species
human
Phospho-EGFR (pTyr1068) and pan-EGFR ELISA Kit, for detection of human phospho-egfr (pTyr1068) and pan-egfr in cell and tissue lysates,
Species
human
Phospho-EGFR (pTyr1045) ELISA Kit, for detection of human phospho-egfr (pTyr1045) in cell and tissue lysates,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-EGFR (PhosphoTyr1173) antibody produced in mouse, clone EM-13,
Species Reactivity
human
Application
western blot
Anti-phospho-EGFR (Tyr1173) Antibody, clone 3E7.2, clone 3E7.2, from mouse,
Species Reactivity
human
Application
immunocytochemistry
western blot
western blot
Monoclonal Anti-EGFR antibody produced in mouse, clone EGFR1,
Species Reactivity
horse, human
Application
flow cytometry
Anti-EGFR antibody, Rabbit monoclonal, clone SP84, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
bovine, frog, human, mouse, pig, rat
Application
immunohistochemistry
western blot
western blot
Anti-EGFR antibody, Rabbit monoclonal, clone SP125, recombinant, expressed in proprietary host, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Gefitinib for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human
Proteins
Product Number
Description
Species
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human
EGFR (L861Q), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human