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122505

2,3-Dihydroxypyridine

Name: 2,3-Dihydroxypyridine
Brand: ALDRICH

95%

Synonym(s):

2,3-Pyridinediol

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About This Item

Empirical Formula (Hill Notation):

C₅H₅NO₂

CAS Number:

16867-04-2

Molecular Weight:

111.10

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24847492

EC Number:

240-887-3

Beilstein/REAXYS Number:

109848

MDL number:

MFCD00006271

Assay:

95%

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Properties

Quality Level

100

assay

95%

mp

245 °C (dec.) (lit.)

SMILES string

Oc1cccnc1O

InChI

1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)

InChI key

GGOZGYRTNQBSSA-UHFFFAOYSA-N

Description

Application

2,3-Dihydroxypyridine(DHP) was used in the synthesis of DHP loaded amberlite XAD-2 via azo coupler. It was used in the synthesis of new macromolecular chelators by loading DHP on cellulose via linkers -NH-CH₂-CH₂-NH-SO₂-C₆H₄-N=N- and -SO₂-C₆H₄-N=N.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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2, 3-Dihydroxypyridine loaded amberlite XAD-2 (AXAD-2-DHP): preparation, sorption-desorption equilibria with metal ions, and applications in quantitative metal ion enrichment from water, milk and vitamin samples.

Venkatesh G, et al.

Microchimica Acta, 149(3-4), 213-221 (2005)

6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H.

Lei Wang et al.

European journal of medicinal chemistry, 156, 680-691 (2018-07-23)

Human immunodeficiency virus (HIV) reverse transcriptase (RT)-associated ribonuclease H (RNase H) remains an unvalidated drug target. Reported HIV RNase H inhibitors generally lack significant antiviral activity. We report herein the design, synthesis, biochemical and antiviral evaluations of a new 6-biphenylmethyl

Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H.

Jayakanth Kankanala et al.

European journal of medicinal chemistry, 141, 149-161 (2017-10-17)

Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) is the only HIV enzymatic function not targeted by current antiviral drugs. Although various chemotypes have been reported to inhibit HIV RNase H, few have shown significant antiviral

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Global Trade Item Number

SKU	GTIN
122505-25G	04061832540894
122505-100G	04061838345530