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139114

(−)-Borneol

Name: (−)-Borneol
Brand: ALDRICH

predominantly endo, 97%

Synonym(s):

endo-(1S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₈O

CAS Number:

464-45-9

Molecular Weight:

154.25

UNSPSC Code:

12352212

NACRES:

NA.22

PubChem Substance ID:

24848391

EC Number:

207-353-1

Beilstein/REAXYS Number:

2038053

MDL number:

MFCD00003759

Assay:

97%

Form:

solid

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Properties

vapor density

5.31 (vs air)

Quality Level

100

vapor pressure

33.5 mmHg ( 25 °C)

assay

97%

form

solid

optical activity

[α]20/D −35.3°, c = 5 in ethanol

bp

210 °C (lit.)

mp

206-208 °C (lit.)

functional group

hydroxyl

SMILES string

[H][C@]12CC[C@](C)([C@H](O)C1)C2(C)C

InChI

1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m0/s1

InChI key

DTGKSKDOIYIVQL-QXFUBDJGSA-N

Description

General description

(-)-Borneol is a bicyclic monoterpene found in essential oils.

Application

(-)-Borneol has been used to study its antiapoptotic, antioxidative and neuroprotective effect in human neuroblastoma cells (SH-SY5Y).

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pictograms

GHS02,GHS07

signalword

Warning

hcodes

H228,H317,H412

pcodes

P210 - P240 - P241 - P273 - P280 - P302 + P352

Hazard Classifications

Aquatic Chronic 3 - Flam. Sol. 2 - Skin Sens. 1

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 2

flash_point_f

150.8 °F

flash_point_c

66 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

危险化学品

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(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.

Granger RE, et al.

Biochemical Pharmacology, 69(7), 1101-1111 (2005)

Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells.

Jinyoung Hur et al.

Pharmaceutical biology, 51(1), 30-35 (2012-11-09)

The β-amyloid (Aβ) peptide aggregation with accompanying oxidative stress plays the major role in the pathogenesis of Alzheimer's disease (AD). Some natural compounds, including borneol, shed promising light on AD treatment. The present study was designed to investigate the antioxidative

[Effect of borneol on intestinal absorption of muscone in rats].

Liang Zou et al.

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(22), 3490-3493 (2013-02-05)

To explore the influence of borneol on intestinal absorption of muscone in rats. An in situ intestinal circulation perfusion experiment was used to study the changes in intestinal absorption kinetics of muscone before and after being compatible with borneol. Compared

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Global Trade Item Number

SKU	GTIN
139114-100G	04061838732651
139114-500G	04061833037799