191884
Hydroxypropyl cellulose
average Mw ~100,000, powder, 20 mesh particle size (99% through)
Synonym(s):
Cellulose & cellulose derivatives
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About This Item
Quality Level
description
biological oxygen demand (BOD) 14,000 ppm
form
powder
autoignition temp.
752 °F
mol wt
average Mw ~100,000
impurities
<5 wt. %
particle size
20 mesh (99% through)
pH
5.0-8.5
interfacial tension mineral oil
12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)
viscosity
65-175 cP, 5 wt. % in H2O(25 °C, Brookfield, spindle #1) (30 rpm)(lit.)
solubility
polar organic solvents: soluble
density
0.5 g/mL at 25 °C (lit.)
SMILES string
N(C)(C)c1cc(c(cc1)C(N)CC)C
InChI
1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3
InChI key
RRHXDYJWVYFMKV-UHFFFAOYSA-N
General description
Hydroxypropyl cellulose (HPC) is a neutral polysaccharide prepared by reacting propylene oxide with alkali cellulose at high temperatures and pressure. It is soluble in water and many polar organic solvents. HPC is widely used as a food additive and in drug delivery systems.
Application
Hydroxypropyl cellulose can be used in the following applications:
- HPC is soluble in organic solvents which makes it suitable for the preparation of polymer gel electrolytes for electrochemical devices. The network-forming ability of HPC can improve the mechanical and electrical properties of gel electrolytes.
- Electrospun hydroxypropyl cellulose nanofibres can be used to develop drug delivery systems for a variety of hydrophobic drugs.
- Hydroxypropylcellulose combined with an effervescent agent like sodium carbonate can be usedas a binder and functional material to prepare floating tablets for thecontrolled release of ofloxacin.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Jeremiah F Kelleher et al.
AAPS PharmSciTech, 21(1), 23-23 (2019-12-14)
The development of oral solid dosage forms, such as tablets that contain a high dose of drug(s), requires polymers and other additives to be incorporated at low levels as possible, to keep the final tablet weight low, and, correspondingly, the
Daniela M Correia et al.
Materials (Basel, Switzerland), 13(10) (2020-05-21)
This study reports a versatile method for the development of cellulose nanocrystals (CNCs) and water-soluble cellulose derivatives (methyl cellulose (MC), hydroxypropyl cellulose (HPC), and sodium carboxymethyl cellulose (NaCMC)) films comprising the ionic liquid (IL) 2-hydroxy-ethyl-trimethylammonium dihydrogen phosphate ([Ch][DHP]) for actuator
Jianjun Yang et al.
International orthopaedics, 37(3), 515-521 (2012-11-28)
The aim of this study was to determine whether hydroxypropylcellulose (HPC) coating of polyethylene terephthalate (PET) artificial ligaments enhances graft osseointegration in the bone tunnel. Thirty New Zealand white rabbits underwent artificial ligament graft transplantation in the bilateral proximal tibia
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 69806-1G | 04061826067253 |
| 69806-5G | 04061832896601 |
| 191884-250G | 04061838760333 |
| 191884-100G | 04061835561599 |
| 191884-5G | 04061838760340 |