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Merck
CN

195812

4-Amino-1-benzylpiperidine

98%

Synonym(s):

1-(Phenylmethyl)-4-piperidinamine

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About This Item

Empirical Formula (Hill Notation):
C12H18N2
CAS Number:
Molecular Weight:
190.28
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
256-620-9
Beilstein/REAXYS Number:
146038
MDL number:
Assay:
98%
Form:
liquid
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Quality Level

assay

98%

form

liquid

refractive index

n20/D 1.543 (lit.)

density

0.933 g/mL at 25 °C (lit.)

functional group

phenyl

SMILES string

NC1CCN(CC1)Cc2ccccc2

InChI

1S/C12H18N2/c13-12-6-8-14(9-7-12)10-11-4-2-1-3-5-11/h1-5,12H,6-10,13H2

InChI key

YUBDLZGUSSWQSS-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

Application

4-Amino-1-benzylpiperidine was used in the preparation of:
  • butyl 4-amino-1-piperidineacetate, key intermediate required for the synthesis of butyl 4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-1-piperidineacetate
  • 5-alkylimino-1,2,4-thiadiazolidine-3-ones, such as 4-ethyl-5-[imino-[1-(phenylmethyl)-4-piperidinyl]]-2-methyl-1,2,4-thiadiazolidin-3-one and 4-benzyl-5-[imino-[1-(phenylmethyl)-4-piperidinyl]]-2-isopropyl-1,2,4-thiadiazolidin-3-one
  • glycyrrhetinic acid derivatives
Reactant for synthesis of:
Highly selective inhibitors of p38a mitogen-activated protein kinase
Antiplasmodial compounds
Dual activity cholinesterase and Aβ-aggregation inhibitors
Muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonists
Photostable near-infrared cyanine dyes
99mTc-labeled piperidine analogues for targeting sigma receptors


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Irrit. 2

Storage Class

10 - Combustible liquids

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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