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Merck
CN

224936

4-(Trifluoromethyl)aniline

99%

Synonym(s):

α,α,α-Trifluoro-p-toluidine, 4-Aminobenzotrifluoride

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About This Item

Linear Formula:
CF3C6H4NH2
CAS Number:
Molecular Weight:
161.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-236-5
Beilstein/REAXYS Number:
1564853
MDL number:
Assay:
99%
Form:
liquid
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Quality Level

assay

99%

form

liquid

refractive index

n20/D 1.483 (lit.)

bp

83 °C/12 mmHg (lit.)

density

1.283 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

Nc1ccc(cc1)C(F)(F)F

InChI

1S/C7H6F3N/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H,11H2

InChI key

ODGIMMLDVSWADK-UHFFFAOYSA-N

Application

4-(Trifluoromethyl)aniline was used in the synthesis of 4-(trialkylmethyl)anilines. It was also used as a synthetic building block.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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A Facile Synthesis of 4-(Trialkylmethyl) anilines by the Reaction of 4-(Trifluoromethyl) aniline with Grignard Reagents.
Synthetic Communications, 27(11), 1975-1980 (1997)
A Sgroi et al.
Biochemical and biophysical research communications, 221(2), 361-367 (1996-04-16)
A gene for the Paracentrotus lividus ribosomal protein S24, called P1-S24, has been isolated and sequenced. Ribosomal protein P1-S24 consists 130 amino acids and has a molecular weight of 14869 Da. Sequence analysis shows a high percentage (90%) identity with
L M Angerer et al.
Developmental biology, 149(1), 27-40 (1992-01-01)
We have identified an mRNA that encodes a protein, SpS24, of the small ribosomal subunit in the sea urchin, Strongylocentrotus purpuratus. RNA blot and in situ hybridization analyses show that the SpS24 gene is active during early oogenesis, downregulated in



Global Trade Item Number

SKUGTIN
224936-10G04061838779311
224936-25G04061838779335
224936-1G04061838779328