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Merck
CN

450561

11-Mercaptoundecanoic acid

95%

Synonym(s):

MUA, MUDA

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About This Item

Linear Formula:
HS(CH2)10CO2H
CAS Number:
Molecular Weight:
218.36
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
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Quality Level

assay

95%

form

solid

mp

46-50 °C (lit.)

SMILES string

OC(=O)CCCCCCCCCCS

InChI

1S/C11H22O2S/c12-11(13)9-7-5-3-1-2-4-6-8-10-14/h14H,1-10H2,(H,12,13)

InChI key

GWOLZNVIRIHJHB-UHFFFAOYSA-N

General description

11-Mercaptoundecanoic acid (MUA) is used as a self-assembled monolayer (SAM) which has a long alkane chain and carboxyl containing thiols. MUA is highly packed and has self-organized surface monolayers. It is a pH responsive ligand which facilitates the dispersion of nanoparticles into water and solvent based media.

Application

MUA as a self-assembled monolayer (SAM) is used as a microfluidic integrated surface plasmon resonance (SPR) for detection and quantification of bacteria in medical diagnostics. It is also used to bio-functionalize the screen printed gold electrodes (SPGEs) that are used for the detection and quantification of dengue. It also forms monolayers on gold nanoparticles (AuNPs) attached via thiol groups. MUA incorporated AuNPs exhibit excellent fluorescence properties which may be used for metal ion detection in serum samples.


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Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Articles

Recent research highlights tunable properties of inorganic nanoparticles, driving interest in optoelectronics.


11-Mercaptoundecanoic acid functionalized gold nanoclusters as fluorescent probes for the sensitive detection of Cu2+ and Fe3+ ions.
Bai Z, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 28(9), 1901-1904 (2017)
Electrochemical lateral flow immunosensor for detection and quantification of dengue NS1 protein.
Sinawang PD, et al.
Biosensors And Bioelectronics, 77(5), 400-408 (2016)
Alexey Ivanov et al.
Talanta, 194, 723-730 (2019-01-06)
Reversible inhibitors of acetylcholinesterase are increasingly applied in the Alzheimer's disease therapy. Their determination with biosensors requires special attention to the enzyme immobilization due to importance of electrostatic and steric factors affecting accessibility of the active site to the substrate



Global Trade Item Number

SKUGTIN
450561-25G04061832323817
450561-5G04061832323824