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Merck
CN

475629

Poly(ethylene glycol) diacrylate

average Mn 250, acrylate, 100 ppm MEHQ as inhibitor

Synonym(s):

Polyethylene glycol, PEG diacrylate

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About This Item

CAS Number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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Product Name

Poly(ethylene glycol) diacrylate, average Mn 250

mol wt

average Mn 250

Quality Level

contains

100 ppm MEHQ as inhibitor

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

refractive index

n20/D 1.463

density

1.11 g/mL at 25 °C

Ω-end

acrylate

α-end

acrylate

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

2-8°C

SMILES string

OCCO.OC(=O)C=C

InChI

1S/C8H10O4/c1-3-7(9)11-5-6-12-8(10)4-2/h3-4H,1-2,5-6H2

InChI key

KUDUQBURMYMBIJ-UHFFFAOYSA-N

General description

Poly(ethylene glycol) diacrylate (PEGDA) is a polyethylene glycol (PEG) based material that can be used for a variety of tissue engineering and drug delivery based applications. It is majorly used as a prepolymer solution that can be used in the formation of a cross-linked polymeric system.

Application

PEGDA can be used in the formation of a UV-cured membrane for potential usage in the separation of carbon dioxide (CO2) based gases. It may also be used in the development of novel injectable biodegradable polymers for a variety of biomedical applications.


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pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 1

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Articles

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Scaffold patterning with poly(ethylene glycol)-based hydrogels for cell presence in 2D and 3D environments on photoactive substrates.


Multifunctional thiols as additives in UV-cured PEG-diacrylate membranes for CO2 separation
Kwisnek L, et al.
Journal of Membrane Science, 369(1-2), 429-436 (2011)
Injectable biodegradable polymer composites based on poly (propylene fumarate) crosslinked with poly (ethylene glycol)-dimethacrylate
He S, et al.
Biomaterials, 21(23), 2389-2394 (2000)
Release of protein from highly cross-linked hydrogels of poly (ethylene glycol) diacrylate fabricated by UV polymerization
Mellott MB, et al.
Biomaterials, 22(9), 929-941 (2001)



Global Trade Item Number

SKUGTIN
475629-100ML04061837888328
475629-500ML04061832361789