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Merck
CN

755842

6-Maleimidohexanoic acid

90% (GC)

Synonym(s):

2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid, 6-Maleimide hexanoic acid, MCA, Maleimidocaproic acid, 6-Maleimidocaproic acid, N-Maleoyl-6-aminocaproic acid, N-(5-Carboxypentyl)maleimide

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About This Item

Empirical Formula (Hill Notation):
C10H13NO4
CAS Number:
Molecular Weight:
211.21
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1532405
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Quality Level

assay

90% (GC)

form

powder

mp

87-92 °C

storage temp.

2-8°C

SMILES string

OC(=O)CCCCCN1C(=O)C=CC1=O

InChI

1S/C10H13NO4/c12-8-5-6-9(13)11(8)7-3-1-2-4-10(14)15/h5-6H,1-4,7H2,(H,14,15)

InChI key

WOJKKJKETHYEAC-UHFFFAOYSA-N

Application

Intermediate for ester and amide linked maleimide monomers
Probe for thiol groups (SH-groups) in membrane proteins.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3



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You-Jun Li et al.
Oncotarget, 6(35), 36943-36954 (2015-10-16)
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) encodes a tumor suppressor gene implicated in the growth of various tumor types including breast cancer. We previously demonstrated that recombinant adenovirus-mediated mda-7/IL-24 expression in the mammary glands of carcinogen-treated (methylnitrosourea, MNU) rats suppressed mammary
D B R K Gupta Udatha et al.
Journal of structural biology, 190(3), 314-327 (2015-04-25)
The catalytic residues in carbohydrate esterase enzyme families constitute a highly conserved triad: serine, histidine and aspartic acid. This catalytic triad is generally located in a very sharp turn of the protein backbone structure, called the nucleophilic elbow and identified
Mohammed Abdelsaid et al.
Life sciences, 118(2), 268-273 (2014-01-23)
We have shown that diabetes causes cerebrovascular remodeling in part by the activation of the endothelin (ET-1) system in a glucose-dependent manner. We also reported increased yet dysfunctional cerebral angiogenesis in diabetes. Here, we tested the hypothesis that dual ET-1



Global Trade Item Number

SKUGTIN
755842-25G04061832909080