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765260

Gold nanoparticles

5 nm diameter, amine functionalized, PEG 3000 coated, OD 50, dispersion in H2O

Synonym(s):

Gold nanoparticles NH2 functionalized, Au NP NH2, Gold Colloid

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About This Item

NACRES:
NA.23
UNSPSC Code:
12162002
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material

PEG 3000

Quality Level

100

form

dispersion in H2O, nanoparticles

packaging

glass bottle of 1 mL

OD

50

diameter

5 nm

pH

6.0-8.0 (25 °C)

solubility

water: miscible

density

1.00 g/cm3

λmax

515 nm

functional group

amine

storage temp.

2-8°C

Application

Amine functionalized, PEG 3000 coated, OD 50, and H2O dispersed gold nanoparticles (5 nm) can be used in the activation of silica nanosphere for the decomposition of formic acid. They may be used in the radiosensitization and imaging of cancer cells.
AuNPs can be potentially immobilized on antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. They can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization, which can be used in the diagnosis of COVID-19.
Functionalized particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.

Features and Benefits

  • Negatively charged siRNA-PEG complex which is attached to positively charged GNPs is easily cleavable in reductive cytosolic environment thus enabling the release of siRNA into cytosol.
  • Decreases the cytotoxicity and increases efficiency of GNPs. PEG increases the stability of the nanoparticles and prevents agglomeration.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ5307
MKCD6399
MKBN9274V

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Articles

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Magnetic Nanoparticles for Cancer Theranostics

The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.

Micro- and Nanofabricated Biomaterials

Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.

Scott H Brewer et al.
Langmuir : the ACS journal of surfaces and colloids, 21(20), 9303-9307 (2005-09-21)
The interaction of bovine serum albumin (BSA) with gold colloids and surfaces was studied using zeta-potential and quartz crystal microbalance (QCM) measurements, respectively, to determine the surface charge and coverage. The combination of these two measurements suggests that BSA binding
Functionalized gold nanoparticles and their biomedical applications
Tiwari, P. M., Vig, K., Dennis, V. A., & Singh, S. R.
Nanomaterials, 1(1), 31-63 (2011)

Global Trade Item Number

SKUGTIN
765260-1ML04061837523441