B3253
Butyrylthiocholine iodide
≥98%
Synonym(s):
(2-Mercaptoethyl)trimethylammonium iodide butyrate
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About This Item
Linear Formula:
(CH3)3N(I)CH2CH2SCOCH2CH2CH3
CAS Number:
Molecular Weight:
317.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
217-475-7
Beilstein/REAXYS Number:
3729509
MDL number:
Assay:
≥98%
Form:
powder
Quality Level
assay
≥98%
form
powder
mp
171-174 °C (lit.)
storage temp.
−20°C
SMILES string
[I-].CCCC(=O)SCC[N+](C)(C)C
InChI
1S/C9H20NOS.HI/c1-5-6-9(11)12-8-7-10(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChI key
WEQAAFZDJROSBF-UHFFFAOYSA-M
General description
Butyrylthiocholine iodide is a sulfur-containing analog of butyrylcholine. It is used as a reagent for the determination of butyrylcholinesterase activity.
Application
- Label-Free and Ultrasensitive Detection of Butyrylcholinesterase: A study demonstrated the use of Mn(II)-based electron spin resonance spectroscopy for the ultrasensitive detection of butyrylcholinesterase, using Butyrylthiocholine iodide as a substrate to quantify enzyme activity in the presence of organophosphorus pesticides, crucial for biochemical assay applications (Tang et al., 2022).
- Novel Nanozyme for Biosensing: Research developed a Co, N co-doped porous carbon-based nanozyme, demonstrating its utility as an oxidase mimic for fluorescence and colorimetric biosensing of butyrylcholinesterase, employing Butyrylthiocholine iodide as a key substrate, relevant in enzyme kinetics analysis (Sun et al., 2022).
- Detection System for Anti-Alzheimer′s Drug Screening: A fluorescent platform was constructed using copper nanoclusters and MnO2 nanosheets for the detection of butyrylcholinesterase activity, utilizing Butyrylthiocholine iodide, which may facilitate the screening of anti-Alzheimer′s drugs and probe cholinergic system interactions (Chen et al., 2022).
- Dual-Channel Detection of Butyrylcholinesterase: A study introduced bifunctional metal-organic frameworks with integrated fluorescence and oxidase activities, developed for dual-channel detection of butyrylcholinesterase using Butyrylthiocholine iodide, enhancing methodologies in biochemical assays (Wang et al., 2022).
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Vida Mirzaie et al.
Drug design, development and therapy, 14, 3589-3599 (2020-09-19)
Human butyrylcholinesterase (BChE) serves as a bio scavenger to counteract organophosphate poisoning. It is also a potential drug candidate in several therapeutic fields. Therefore, in the present study, we constructed a new dual-promoter plasmid consisting of Cytomegalovirus (CMV) and human
Gabriela Fernandes et al.
The journal of adhesive dentistry, 22(3), 265-274 (2020-05-22)
To investigate whether dental adhesives modified with polyacrylic acid copper iodide particles could inhibit esterase activity in vitro and the copper release rate from resin matrices, as well as the correlation between the two variables. Different concentrations of copper iodide
Cristobal Narvaez et al.
Chemosphere, 135, 75-82 (2015-04-29)
Inhibition of blood esterase activities by organophosphate (OP) pesticides has been used as a sensitive biomarker in birds. Furthermore, compared to mammalian vertebrates, less is known about the role of these enzyme activities in the digestive tracts of non-mammalian vertebrates
Global Trade Item Number
| SKU | GTIN |
|---|---|
| B3253-25G | 04061833427460 |
| B3253-5G | 04061833427477 |