H1384
Hypotaurine
≥98% (TLC)
Synonym(s):
2-Aminoethanesulfinic acid
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About This Item
Empirical Formula (Hill Notation):
C2H7NO2S
CAS Number:
Molecular Weight:
109.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥98% (TLC)
Quality Level
assay
≥98% (TLC)
color
white to off-white
solubility
H2O: 100 mg/mL
SMILES string
NCCS(O)=O
InChI
1S/C2H7NO2S/c3-1-2-6(4)5/h1-3H2,(H,4,5)
InChI key
VVIUBCNYACGLLV-UHFFFAOYSA-N
Application
Hypotaurine has been used as a supplement in fertilization medium (Fert- tyrode albumin lactate pyruvate (TALP)), which used in in-vitro fertilization and evaluation of embryo development. It is also used as a H2S scavenger.
Biochem/physiol Actions
Hypotaurine, a cystamine analog, is the precursor for taurine synthesis. It can act as an antioxidant and singlet oxygen scavenger, thereby protecting cells from oxidative damage. Hypotaurine is reported to play an important role in the maintenance and stimulation of sperm motility and also in vitro fertilization and embryo development.
Antioxidant that binds hydroxyl radicals. Endogenous inhibitory neuromodulator that is blocked by strychnine and picrotoxin. Inhibits the Na2+-dependent transport of GABA and β-alanine. It is a degradation product of cysteine and a precursor of taurine.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Improvement of bovine semen quality by removal of membrane-damaged sperm cells with DNA aptamers and magnetic nanoparticles.
Farini V L, et al.
Journal of Biotechnology, 229, 33-41 (2016)
Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins.
Hoffstrom BG
Nature Chemical Biology, 6(12), 900-900 (2010)
Satoshi Sugimura et al.
Scientific reports, 7(1), 6815-6815 (2017-07-30)
During antral folliculogenesis, developmental competence of prospective oocytes is regulated in large part by the follicular somatic component to prepare the oocyte for the final stage of maturation and subsequent embryo development. The underlying molecular mechanisms are poorly understood. Oocytes
Global Trade Item Number
| SKU | GTIN |
|---|---|
| H1384-100MG | 04061835208715 |
| H1384-1G | 04061835208739 |
| H1384-250MG | 04061835208746 |
| H1384-10MG | 04061835208722 |