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790981P

Avanti

14:0 PE-DTPA (Gd)

Avanti Research - A Croda Brand

Synonym(s):

1,2-ditetradecanoyl-sn-glycero-3-phosphoethanolamine- N-diethylenetriaminepentaacetic acid (gadolinium salt); DMPE-DTPA (Gd)

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About This Item

Empirical Formula (Hill Notation):
C47H90GdN6O17P
CAS Number:
Molecular Weight:
1199.47
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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Product Name

14:0 PE-DTPA (Gd), 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid (gadolinium salt), powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (790981P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 790981P

lipid type

phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

14:0 PE-DTPA (Gd) has been used as a paramagnetic lipid to probe the orientation of a membrane protein in respect to the phospholipid bilayer membrane.
Lipid nanoparticles containing DMPE-DTPA(Gd) provide high quality contrast enhanced vascular MRI at 97% reduced dose of Gd and do not rely on renal clearance. Structure as shown by Cormode, D.P. et al.

Packaging

5 mL Amber Glass Screw Cap Vial (790981P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Storage Class

11 - Combustible Solids

flash_point_f

No data available

flash_point_c

No data available



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Assembly of phospholipid nanodiscs of controlled size for structural studies of membrane proteins by NMR
Hagn F, et al.
Nature Protocols, 13(1), 79-79 (2018)
Nanocrystal core high-density lipoproteins: a multimodality contrast agent platform.
Cormode DP, et al.
Nano Letters, 8, 3715-3723 (2008)
David P Cormode et al.
Nano letters, 8(11), 3715-3723 (2008-10-23)
High density lipoprotein (HDL) is an important natural nanoparticle that may be modified for biomedical imaging purposes. Here we developed a novel technique to create unique multimodality HDL mimicking nanoparticles by incorporation of gold, iron oxide, or quantum dot nanocrystals



Global Trade Item Number

SKUGTIN
790981P-5MG04061835189649