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840034P

Avanti

16:0-18:1 PS (POPS)

Avanti Polar Lipids

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Synonym(s):
1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); POPS; PS(16:0/18:1(9Z)); 110669
Empirical Formula (Hill Notation):
C40H75NO10PNa
CAS Number:
321863-21-2
Molecular Weight:
783.99
NACRES:
NA.25

description

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840034P-10mg)
pkg of 2 × 100 mg (840034P-200mg)
pkg of 5 × 100 mg (840034P-500mg)
pkg of 1 × 25 mg (840034P-25mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

Related Categories

General description

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.

Application

16:0-18:1 PS (POPS) has been used:
  • in phospholipid mixture for nanodisc preparation
  • in liposome preparation
  • in lipid vesicle preparation for surface plasmon resonance (SPR) analysis

Biochem/physiol Actions

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the ability to create new memories, to focus attention, to reason and solve problems and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.

Packaging

5 mL Clear Glass Sealed Ampule (840034P-10mg)
5 mL Clear Glass Sealed Ampule (840034P-200mg)
5 mL Clear Glass Sealed Ampule (840034P-25mg)
5 mL Clear Glass Sealed Ampule (840034P-500mg)

also commonly purchased with this product

Product No.
Description
Pricing

700000P

Cholesterol (ovine), Avanti Polar Lipids

840033P

14:0 PS, Avanti Polar Lipids

840035P

18:1 PS (DOPS), Avanti Polar Lipids

840457P

16:0-18:1 PG, Avanti Polar Lipids

840475P

18:1 (Δ9-Cis) PG, Avanti Polar Lipids

840857P

16:0-18:1 PA, powder

850345P

14:0 PC (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine, powder

850355P

16:0 PC (DPPC), Avanti Polar Lipids

850365P

18:0 PC (DSPC), Avanti Polar Lipids

850375P

18:1 (Δ9-Cis) PC (DOPC), Avanti Polar Lipids

850457C

16:0-18:1 PC, Avanti Polar Lipids

850457P

16:0-18:1 PC, Avanti Polar Lipids

850725P

18:1 (Δ9-Cis) PE (DOPE), Avanti Polar Lipids

850757P

16:0-18:1 PE, Avanti Polar Lipids

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3, 4, 5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain
Kim E, et al.
Cellular Signalling, 51, 130-138 (2018)
Fluorophore Labeling, Nanodisc Reconstitution and Single-molecule Observation of a G Protein-coupled Receptor
Lamichhane R, et al.
Bio-protocol, 7(12) (2017)
Carina Drechsler et al.
Biophysical journal, 115(8), 1509-1517 (2018-09-30)
Lipid asymmetries between the outer and inner leaflet of the lipid bilayer exist in nearly all biological membranes. Although living cells spend great effort to adjust and maintain these asymmetries, little is known about the biophysical phenomena within asymmetric membranes
Josef Melcr et al.
Journal of chemical theory and computation, 16(1), 738-748 (2019-11-26)
Phosphatidylserine (PS) lipids are important signaling molecules and the most common negatively charged lipids in eukaryotic membranes. The signaling can be often regulated by calcium, but its interactions with PS headgroups are not fully understood. Classical molecular dynamics (MD) simulations
Adsorption of O-phospho-L-serine and L-serine onto poorly crystalline apatite
Benaziz L, et al.
Journal of Colloid and Interface Science, 238(1), 48-53 (2001)
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