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850458P

Avanti

16:0-18:2 PC

Avanti Research™ - A Croda Brand

Synonym(s):

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; PC(16:0/18:2(9Z,12Z))

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About This Item

Empirical Formula (Hill Notation):
C42H80NO8P
CAS Number:
159701-21-0
Molecular Weight:
758.06
MDL number:
MFCD00082428
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

16:0-18:2 PC, 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (850458P-200mg), pkg of 1 × 25 mg (850458P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850458P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI key

JLPULHDHAOZNQI-ZTIMHPMXSA-N

General description

16:0-18:2 PC or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine is a glycerophospholipid, with substitution of palmitic acid and linolenic acid at sn-1 and sn-2 positions of the glycerol backbone, respectively.

Application

16:0-18:2 PC or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine:
  • has been used in liposomes for standard cell-free translation
  • has been used in the extraction of serum lipids and in peroxisome proliferator-activated receptor-δ (PPAR-δ) assay
  • might be used to study the effects of phosphatidylcholines (PCs) on lubrication of damaged mesothelium

Packaging

5 mL Clear Glass Sealed Ampule (850458P-200mg)
5 mL Clear Glass Sealed Ampule (850458P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class

11 - Combustible Solids

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Certificates of Analysis (COA)

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Francesca Bodega et al.
Respiratory physiology & neurobiology, 203, 116-120 (2014-08-17)
Effect of time and phosphatidylcholines (PCs) on lubrication of damaged mesothelium has been investigated. Marked increase in coefficient of kinetic friction (μ) of pleural specimens after mesothelial blotting and rewetting decreased by 23.4±3.5%, 41.8±3.8%, and 40.5±2.7% after 30min, 1h, and
Lindsay Kosack et al.
Scientific reports, 7(1), 11289-11289 (2017-09-14)
Lipid metabolism is increasingly being appreciated to affect immunoregulation, inflammation and pathology. In this study we found that mice infected with lymphocytic choriomeningitis virus (LCMV) exhibit global perturbations of circulating serum lipids. Mice lacking the lipid-sensing surface receptor triggering receptor
Eikan Mishima et al.
Journal of the American Society of Nephrology : JASN, 31(2), 280-296 (2019-11-27)
Ferroptosis, nonapoptotic cell death mediated by free radical reactions and driven by the oxidative degradation of lipids, is a therapeutic target because of its role in organ damage, including AKI. Ferroptosis-causing radicals that are targeted by ferroptosis suppressors have not
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Global Trade Item Number

SKUGTIN
850458P-200MG04061835227327
850458P-25MG04061835227334