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860595P

Avanti

C17 Lactosyl(β) Ceramide (d18:1/17:0)

Avanti Research™ - A Croda Brand

Synonym(s):

D-Lactosyl-β-1,1′-N-Heptadecanoyl-D-erythro-Sphingosine

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About This Item

Empirical Formula (Hill Notation):
C47H89NO13
CAS Number:
1354699-26-5
Molecular Weight:
876.21
MDL number:
MFCD24849259
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

C17 Lactosyl(β) Ceramide (d18:1/17:0), Avanti Research™ - A Croda Brand 860595P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (860595P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860595P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI

1S/C47H89NO13/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-39(52)48-35(36(51)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)34-58-46-44(57)42(55)45(38(33-50)60-46)61-47-43(56)41(54)40(53)37(32-49)59-47/h28,30,35-38,40-47,49-51,53-57H,3-27,29,31-34H2,1-2H3,(H,48,

InChI key

RXEAEJDDQFAFLW-NMZPIEEZSA-N

General description

Lactosylceramide (LacCer) is a glycosphingolipid. It consists of a hydrophobic ceramide lipid and a hydrophilic sugar moiety. LacCer is expressed abundantly in the nervous system and myelin sheath.

Biochem/physiol Actions

Lactosylceramide (LacCer) is a structural and signaling lipid. It is implicated in signal transduction, cell adhesion and host-tissue pathogen interactions. LacCer modulates cell proliferation and apoptosis. It is involved in regulating cellular stress response and microbial pathogenesis. LacCer regulates innate immune responses. It helps in microbial attachment and also acts as an adhesion receptor for pathogens.

Packaging

5 mL Amber Glass Screw Cap Vial (860595P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Regulatory Information

涉药品监管产品

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Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharide, 191, 106-114 (2009)
Jarod A Fincher et al.
Scientific reports, 9(1), 17508-17508 (2019-11-27)
Neutral lipids have been implicated in a host of potentially debilitating human diseases, such as heart disease, type-2 diabetes, and metabolic syndrome. Matrix-assisted laser desorption ionization (MALDI), the method-of-choice for mass spectrometry imaging (MSI), has led to remarkable success in

Global Trade Item Number

SKUGTIN
860595P-5MG04061835318438