05-168
Anti-TNFα Antibody, clone MPG-XT3
clone MPG-XT3, Upstate®, from rat
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
MPG-XT3, monoclonal
Application:
Neutral
Citations:
13
biological source
rat
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
MPG-XT3, monoclonal
species reactivity
mouse
manufacturer/tradename
Upstate®
technique(s)
neutralization: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... TNF(7124)
General description
17 kDa
The concentration of antibody needed to neutralize the bioactivity of TNF-α will depend on the cell type, the incubation conditions, and the biological response studied.
Immunogen
Recombinant murine TNF-α
Application
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
This Anti-TNFalpha Antibody, clone MPG-XT3 is validated for use in NEUT for the detection of TNFα.
Biochem/physiol Actions
mouse TNF-α; does not recognize human or rat TNF-α
Physical form
0.01M Tris-glycine, 0.15M NaCl, pH 7.4
DEAE chromatography
Format: Purified
Preparation Note
2 years at -20°C
Analysis Note
routinely used to neutralize 50% of the cytotoxic effect of recombinant mouse TNF-α on actinomycin D treated L929 cells.
Other Notes
Replaces: 04-1114
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
新产品
This item has
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Cytokine mRNA in the central nervous system of SCID mice infected with Toxoplasma gondii: importance of T-cell-independent regulation of resistance to T. gondii.
Hunter, C A, et al.
Infection and Immunity, 61, 4038-4044 (1993)
TNF-alpha is the critical mediator of the cyclic AMP-induced apoptosis of CD8+4+ double-positive thymocytes.
Guevara Pati??o, et al.
Journal of Immunology, 164, 1689-1694 (2019)
C K Yu et al.
International archives of allergy and immunology, 112(1), 73-82 (1997-01-01)
Dermatophagoides farinae (Der f) is one of the most common species of dust mites that induce asthma and allergic rhinitis. We have reported that Der f challenge on sensitized mice elicited a distinct type of hypersensitivity, called early-type hypersensitivity (ETH)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 05-168 | 04053252672323 |