05-449
Anti-Bin1 Antibody, clone 99D
clone 99D, Upstate®, from mouse
Synonym(s):
Anti-AMPH2, Anti-AMPHL, Anti-CNM2, Anti-SH3P9
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
99D, monoclonal
Application:
IHC, IP, WB
Citations:
11
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
99D, monoclonal
species reactivity
rat, human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... BIN1(274)
mouse ... Bin1(30948)
General description
56kDa
Immunogen
Partial fusion protein corresponding to amino acids 189-398 of human Bin1. Clone 99D
Application
Anti-Bin1 Antibody, clone 99D is an antibody against Bin1 for use in IP, WB, IH.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
BCL2 & Inhibition
Biochem/physiol Actions
Bin1
Physical form
0.1M Tris-glycine, pH 7.4, containing 0.05% sodium azide
Format: Purified
Protein G Chromatography
Preparation Note
1 year at -20°C
Analysis Note
routinely evaluated by immunoblot on RIPA lysate of C2C12 cells.
Other Notes
Due to license agreement restrictions, this product cannot be purchased for resale.
Replaces: MAB4131
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Suppression of MEK/ERK signalling by Myc: role of Bin-1.
Telfer, JF; Urquhart, J; Crouch, DH
Cellular Signalling null
R Wechsler-Reya et al.
Cancer research, 57(15), 3258-3263 (1997-08-01)
BIN1 is a putative tumor suppressor that was identified in a genetic screen for polypeptides that interact with the MYC oncoprotein. Using a set of six monoclonal antibodies, we identified and examined biochemical features and localization of cellular BIN1. Epitope
Maxime Sartori et al.
Acta neuropathologica, 138(4), 631-652 (2019-05-09)
The bridging integrator 1 gene (BIN1) is a major genetic risk factor for Alzheimer's disease (AD). In this report, we investigated how BIN1-dependent pathophysiological processes might be associated with Tau. We first generated a cohort of control and transgenic mice